Evidence map›Paper›PMID 33601465›Full record

ReviewRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2021

Effects of Hydrosalpinx on Endometrial Implantation Failures: Evaluating Salpingectomy in Women Undergoing in vitro fertilization.

Antonio Palagiano, Mauro Cozzolino, Filippo Maria Ubaldi, Chiara Palagiano, Maria Elisabetta Coccia

Open access · diamondAbstract readReview
In one paragraph

Review in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  6. Imaging of endometriosis-related infertility.Abdominal radiology (New York) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Antonio PalagianoDepartment of General and Specialized Surgery for Women and Children, Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy.ORCID 0000-0001-8716-5323
Mauro CozzolinoDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, United States.ORCID 0000-0002-5929-2357
Filippo Maria UbaldiGENERA Centre for Reproductive Medicine, Clinica Valle Giulia, Roma, Italy.ORCID 0000-0002-6894-2147
Chiara PalagianoUniversità Campus Bio-Medico, Romq, Italy.ORCID 0000-0001-8716-5323
Maria Elisabetta CocciaDepartment of Biomedical, Experimental and Clinical Sciences, Division of Obstetrics and Gynecology, Università degli Studi di Firenze, Azienda Ospedaliero Universitaria Careggi, Firenze, Italy.ORCID 0000-0001-5294-129X
Azienda Ospedaliero-Universitaria Careggi · ITClinica Valle Giulia · ITUniversidad Rey Juan Carlos · ESUniversità Campus Bio-Medico · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrosalpinx is a disease characterized by the obstruction of the salpinx, with progressive accumulation in the shape of a fluid-filled sac at the distal part of the tuba uterina, and closed to the ovary. Women with hydrosalpinges have lower implantation and pregnancy rates due to a combination of mechanical and chemical factors thought to disrupt the endometrial environment. Evidence suggests that the presence of hydrosalpinx reduces the rate of pregnancy with assisted reproductive technology. The main aim of the present is review to make an overview of the possible effects of hydrosalpinx on in vitro fertilization (IVF). We conducted a literature search on the PubMed, Ovid MEDLINE, and Google Scholar data bases regarding hydrosalpinx and IVF outcomes. Hydrosalpinx probably has a direct toxic effect on sperm motility and on the embryos. In addition, the increasing liquid inside the salpinges could alter the mechanisms of endometrial receptivity. The window of endometrial receptivity is essential in the implantation of blastocysts, and it triggers multiple reactions arising from the endometrium as well as the blastocysts. Hydrosalpinx could influence the expression of

Indexed as

Embryo ImplantationFertilization in VitroSalpingectomyTreatment FailureBlastocystEndometriumFallopian Tube DiseasesFemaleGene ExpressionHomeobox A10 ProteinsHumansInfertility, FemalePregnancyHomeobox A10 Proteins

Identifiers

PMID33601465
PMCPMC10183881
OpenAlexW3129671839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.