ArticleSleep medicine2021
Insomnia as a predictor of diagnosed memory problems: 2006-2016 Health and Retirement Study.
Article in Sleep medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Sleep disorders and the risk of cognitive decline or dementia: an updated systematic review and meta-analysis of longitudinal studies.Journal of neurology · 2025Pooled it
- Are sleep disturbances modifiable risk factors for mild cognitive impairment and dementia? A systematic review of large studies.Sleep & breathing = Schlaf & Atmung · 2025Pooled it
- Efficacy and safety of Kami Guibi-tang in older adults with insomnia and memory complaints: a randomized, double-blind, placebo-controlled pilot trial.BMC complementary medicine and therapies · 2026Trial
- Perceived Neighborhood Disorder, Health Behaviors, and Inflammation Among Older Adults: A Mediation Analysis.Journal of aging and health · 2026Article
- A Qualitative Exploration of Factors Affecting Sleep Experiences Among Older Adults in a Resource-Challenged Urban Community.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Untreated obstructive sleep apnea and accelerated cognitive decline over 10 years.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Immune cell subsets linking insomnia trajectories and incident cognitive impairment: a prospective cohort study.BMC medicine · 2026Article
- Article
- Quantifying the population-level impact of insomnia on dementia among older adults in the United States.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Skin color stratification and sleep duration: Evidence from a nationally representative sample.Sleep health · 2026Article
- Study on the Mechanism of Mongolian Medical Warm Acupuncture in Regulating Biological Clock Genes and Improving Sleep in Insomniac Rats.Current medicinal chemistry · 2026Article
- Circadian Rhythms in Aging and Age-Related Neurogenerative Disease.Current sleep medicine reports · 2025Article
- Individual Sleep Problems Are Associated With an Accelerated Decline in Multiple Cognitive Functions in Older Adults.Journal of sleep research · 2025Article
- Association between longitudinal trajectories of insomnia symptoms and subsequent cognitive decline: a prospective cohort study.Age and ageing · 2025Article
- Untreated insomnia as a contributor to geographic disparities in risk for Alzheimer's disease and related dementias.Sleep health · 2025Article
- Depressive and Insomnia Symptoms Among Older Adults With Different Chronic Pain Trajectories: A Network Analysis Based on Observation Over an Eight-Year Period.Depression and anxiety · 2025Article
- Insomnia symptoms and the risk of all-cause mortality among stroke survivors.BMC public health · 2024Article
- Insomnia symptoms and increased risk of all-cause mortality by age and sex.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Poor sleep quality, dementia status and their association with all-cause mortality among older US adults.Aging · 2024Article
- Examining Anxiety and Insomnia in Internship Students and Their Association with Internet Gaming Disorder.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate the longitudinal relationship in insomnia symptoms over time with incident memory problems and dementia diagnoses among U.S. adults aged 65 years and older.
methodsSecondary analyses were performed on 9518 elderly participants (≥65 years) who completed the 2006 wave of the Health and Retirement Study (HRS) and were followed-up to determine if insomnia symptom scores (2006-2014) were associated with time-to-onset of [1] physician-diagnosed "memory-related disease", "Alzheimer's disease" and/or "dementia, senility or any other serious memory impairment" and [2] diagnosis of dementia based on HRS-specific criteria. Cox proportional hazards models were constructed adjusting for socio-demographic, lifestyle, and health characteristics.
resultsIn fully adjusted models, severe insomnia symptoms were associated with increased risk of physician-diagnosed memory problems. Individuals reporting any change (increase or decrease) in insomnia symptoms during the 2006-2010 period were more likely to be diagnosed with dementia based on HRS criteria. Finally, those who experienced an increase in the severity of insomnia symptoms over time exhibited 41-72% increased risks of physician-diagnosed memory problems and 45-58% increased risks of dementia diagnosis based on HRS criteria.
conclusionsWhen severe insomnia symptoms increased over time, physician-diagnosed memory problems and dementia diagnoses also increased among U.S. elderly people over a 10-year follow-up period. More studies are required to confirm these findings using large prospective cohort designs and validated tools.
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