Evidence map›Paper›PMID 33600743›Full record

ArticleAmerican journal of respiratory cell and molecular biology2021

Endothelial Cell Protein C Receptor Deficiency Attenuates

Shiva Keshava, Jhansi Magisetty, Torry A Tucker, Weshely Kujur, Sachin Mulik, Charles T Esmon, Steven Idell, L Vijaya Mohan Rao, Usha R Pendurthi

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Mechanisms of lung endothelial cell injury and survival in pulmonary arterial hypertension.American journal of physiology. Lung cellular and molecular physiology · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Update on Novel Targeted Therapy for Pleural Organization and Fibrosis.International journal of molecular sciences · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shiva KeshavaDepartment of Cellular and Molecular Biology.
Jhansi MagisettyDepartment of Cellular and Molecular Biology.
Torry A TuckerDepartment of Cellular and Molecular Biology.
Weshely KujurDepartment of Pulmonary Immunology, The University of Texas Health Science Center at Tyler, Tyler, Texas; and.
Sachin MulikDepartment of Pulmonary Immunology, The University of Texas Health Science Center at Tyler, Tyler, Texas; and.
Charles T EsmonCoagulation Biology Laboratory, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma.
Steven IdellDepartment of Cellular and Molecular Biology.
L Vijaya Mohan RaoDepartment of Cellular and Molecular Biology.
Usha R PendurthiDepartment of Cellular and Molecular Biology.
The University of Texas Health Science Center at Tyler · USOklahoma Medical Research Foundation · US

Funding

Delivery of PAI-1-targeted intrapleural fibrinolytic therapy for empyemaR01HL130402 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI FLOROVA, GALINA, IDELL, STEVEN · 2017 to 2024
$3.8M
Membrane Phospholipids: The Key Regulators of Tissue Factor Encryption/DecryptionR01HL124055 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI LELLA, VIJAYA MOHAN RAO · 2015 to 2023
$3.3M
Factor VIIa Interaction with Endothelial Cell Protein C ReceptorR01HL107483 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI LELLA, VIJAYA MOHAN RAO · 2012 to 2019
$2.9M
Myocardin in the pathogenesis of pleural remodelingR01HL142853 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI IDELL, STEVEN, IKEBE, MITSUO · 2019 to 2022
$1.9M
Fibrinolytic Proteases, meso-mesenchymal transition and pleural remodelingR01HL130133 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI TUCKER, TORRY ALLE · 2017 to 2021
$1.8M
NHLBI NIH HHS R01 HL107483NHLBI NIH HHS R01 HL124055NHLBI NIH HHS R01 HL130133NHLBI NIH HHS R01 HL130402NHLBI NIH HHS R01 HL142853
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBacterial LoadCells, CulturedDisease Models, AnimalEndothelial Protein C ReceptorFemaleFibrosisHost-Pathogen InteractionsHumansLungMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutNeutrophil InfiltrationEndothelial Protein C ReceptorProcr protein, mouseendothelial protein C receptormesotheliumpleural fibrosisStreptococcus pneumoniae

Identifiers

PMID33600743
PMCPMC8008801
OpenAlexW3131923037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.