Evidence map›Paper›PMID 33600486›Full record

ArticlePLoS pathogens2021

Preexisting and inducible endotoxemia as crucial contributors to the severity of COVID-19 outcomes.

Ilja L Kruglikov, Philipp E Scherer

Abstract read
In one paragraph

Article in PLoS pathogens, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Biomolecules · 2024
    Article
  6. Is the endotoxin-complement cascade the major driver in lipedema?Trends in endocrinology and metabolism: TEM · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Adipose 'neighborhoods' collaborate to maintain metabolic health.Current opinion in genetics & development · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Pathophysiology of cellulite: Possible involvement of selective endotoxemia.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ilja L KruglikovScientific Department, Wellcomet GmbH, Karlsruhe, Germany.ORCID 0000-0002-4031-8203
Philipp E SchererTouchstone Diabetes Center, Department of Internal Medicine, Dallas, Texas, United States of America.ORCID 0000-0003-0680-3392

Funding

The role of AgRP/Auga-ALK pathway in FGF21's brain action on agingP01AG051459 · NIA · YALE UNIVERSITY · PI VISHWA DEEP DIXIT · 2016 to 2026
$25.7M
Novel Mechanisms Regulating the Adipocyte-Brain-Hepatocyte AxisP01DK088761 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI SCHERER, PHILIPP E · 2010 to 2019
$17.4M
Adiponectin, A Protein Secreted From Adipose TissueR01DK055758 · NIDDK · YESHIVA UNIVERSITY · PI SCHERER, PHILIPP E · 2000 to 2024
$10.9M
Generation of Novel Genetic Tools to Study Cellular Heterogeneity in Adipose TissuesRC2DK118620 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI GUPTA, RANA K, SCHERER, PHILIPP E · 2019 to 2023
$7.0M
White Adipose Tissue Physiology, Mitochondrial Function and AdiponectinR01DK099110 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI PHILIPP E SCHERER · 2013 to 2026
$6.7M
NIA NIH HHS P01 AG051459NIDDK NIH HHS P01 DK088761NIDDK NIH HHS R01 DK055758NIDDK NIH HHS R01 DK099110NIDDK NIH HHS RC2 DK118620
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Disease SusceptibilityEndotoxemiaHumansLipopolysaccharidesSeverity of Illness IndexLipopolysaccharides

Identifiers

PMID33600486
PMCPMC7891777

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.