ArticlePreventing chronic disease2021
Racial Residential Segregation and Colorectal Cancer Mortality in the Mississippi Delta Region.
Article in Preventing chronic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Spatiotemporal Modeling of Premature Mortality in Mississippi: A County-Level Analysis of Years of Potential Life Lost, 2015-2025.Preventing chronic disease · 2026Article
- Multilevel insights into obesity, race/ethnicity, and survival in early-onset colorectal cancer in Georgia.Cancer causes & control : CCC · 2026Article
- Review
- Persistent Poverty, Rural Location, and Racial Segregation Are Factors in Colorectal Cancer Screening in Low-Income and Uninsured Populations.Journal of the advanced practitioner in oncology · 2025Article
- Opportunities, challenges, and future directions for simulation modeling the effects of structural racism on cancer mortality in the United States: a scoping review.Journal of the National Cancer Institute. Monographs · 2023Article
- Tools to Measure the Impact of Structural Racism and Discrimination on Gastrointestinal and Hepatology Disease Outcomes: A Scoping Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Article
- Association of racial residential segregation with all-cause and cancer-specific mortality in the reasons for geographic and racial differences in stroke (REGARDS) cohort study.SSM - population health · 2023Article
- Neighborhood deprivation, racial segregation and associations with cancer risk and outcomes across the cancer-control continuum.Molecular psychiatry · 2023Review
- Cancer Screening Prevalence and Associated Factors Among US Adults.Preventing chronic disease · 2022Article
- The Rural Household Production of Health Approach: Applying Lessons from Zambia to Rural Cancer Disparities in the U.S.International journal of environmental research and public health · 2022Article
- Racial and Ethnic Disparities in Cancer Occurrence and Outcomes in Rural United States: A Scoping Review.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
introductionFew studies have examined the effects of racial segregation on colorectal cancer (CRC) outcomes, and none has determined whether rurality moderates the effect of racial segregation on CRC mortality. We examined whether the effect of segregation on CRC mortality varied by rurality in the Mississippi Delta Region, an economically distressed and historically segregated region of the United States.
methodsWe used data from the US Census Bureau and the 1999-2018 Surveillance, Epidemiology, and End Results (SEER) program to estimate mixed linear regression models in which CRC mortality rates among Black and White residents in Delta Region counties (N = 252) were stratified by rurality and regressed on White-Black residential segregation indices and 4 socioeconomic control variables.
resultsAmong Black residents, CRC mortality rates in urban counties were a function of a squared segregation term (b = 162.78, P = .01), indicating that the relationship between segregation and CRC mortality was U-shaped. Among White residents, main effects of annual household income (b = 29.01, P = .04) and educational attainment (b = 34.58, P = .03) were associated with CRC mortality rates in urban counties, whereas only annual household income (b = 19.44, P = .04) was associated with CRC mortality rates in rural counties. Racial segregation was not associated with CRC mortality rates among White residents.
conclusionOur county-level analysis suggests that health outcomes related to racial segregation vary by racial, contextual, and community factors. Segregated rural Black communities may feature stronger social bonds among residents than urban communities, thus increasing interpersonal support for cancer prevention and control. Future research should explore the effect of individual-level factors on colorectal cancer mortality.
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