Evidence map›Paper›PMID 33600238›Full record

ArticleViral immunology

Modular Approaches to Understand the Immunobiology of Human Immunodeficiency Virus Latency.

Gideon Wolf, Nevil J Singh

Open access · greenAbstract read
In one paragraph

Article in Viral immunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gideon WolfDepartment of Microbiology & Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Nevil J SinghDepartment of Microbiology & Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
University of Maryland, Baltimore · US

Funding

Mechanisms maintaining the self-awareness of peripheral T cellsR21AI149076 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SINGH, NEVIL JOHN · 2020 to 2021
$425k
NIAID NIH HHS R21 AI149076
6 · The paper itself

Abstract

Despite advances in slowing the progression of acquired immunodeficiency syndrome (AIDS), there is no viable cure for human immunodeficiency virus (HIV). The challenge toward a cure is mainly the formation and maintenance of a latent reservoir of cells that harbor the virus in both replication-competent and replication-defective states. This small niche of quiescent cells has been identified to reside primarily in quiescent and memory CD4

Indexed as

HIV-1HIV InfectionsAnimalsCD4-Positive T-LymphocytesMiceVirus LatencyVirus ReplicationCytokine MilieuHIV latencyHIV modelsmouse modelsT cell dynamicsT cell migration

Identifiers

PMID33600238
PMCPMC8392075
OpenAlexW3131055593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.