ArticleBreast cancer research and treatment2021
Association between physical activity and subsequent cardiovascular disease among 5-year breast cancer survivors.
Article in Breast cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Effectiveness of aerobic exercise intervention on cardiovascular disease risk in female breast cancer: a systematic review with meta-analyses.BMC public health · 2024Pooled it
- Association of change in physical activity with use of outpatient specialist care and hospitalisations among breast cancer survivors with type 2 diabetes in Sweden.British journal of cancer · 2025Article
- Landscape of Physical Activity and Quality of Life Research in Breast Cancer Survivors: Topic Modeling Analysis.Journal of clinical medicine · 2025Article
- Cardio-oncology rehabilitation and exercise: evidence, priorities, and research standards from the ICOS-CORE working group.European heart journal · 2025Review
- Early Rhythm Control of Atrial Fibrillation in Cancer Survivors: A Nationwide Population-Based Study.Journal of the American Heart Association · 2025Observational
- Exercise Prescription in Cardio-Oncology.Journal of clinical medicine · 2025Review
- Patient engagement strategies in digital health interventions for cancer survivors: A scoping review.PLOS digital health · 2025Article
- Associations of a previous diagnosis of cancer and/or cardiovascular disease with current physical activity levels in Korean adults.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Exercise and cardiovascular health among breast cancer survivors: a scoping review of current observational evidence.Cardio-oncology (London, England) · 2025Review
- Life's Essential 8 and Cardiovascular Disease in Breast Cancer Survivors.Current cardiology reports · 2025Review
- Cardiovascular disease risk and associated physical activity factors in gastrointestinal cancer survivors.BMC public health · 2024Article
- Associations of cholecystectomy with metabolic health changes and incident cardiovascular disease: a retrospective cohort study.Scientific reports · 2024Article
- Cardiac health in breast cancer (CHiB): protocol for a single-centre, randomised controlled trial.BMJ open sport & exercise medicine · 2024Article
- Current Evidence on the Benefit of Exercise in Cancer Patients: Effects on Cardiovascular Mortality, Cardiotoxicity, and Quality of Life.Reviews in cardiovascular medicine · 2023Review
- Disparities in physical activity in adolescent and young adult cancer survivors.Journal of cancer survivorship : research and practice · 2023Article
- Changes in body composition and subsequent cardiovascular disease risk among 5-year breast cancer survivors.Frontiers in cardiovascular medicine · 2023Article
- Can We Mitigate Coronary Heart Disease Risk in Patients with Cancer?Current atherosclerosis reports · 2022Review
- Pre-Diagnosis Diet and Physical Activity and Risk of Cardiovascular Disease Mortality among Female Cancer Survivors.Cancers · 2022Article
- Physical Activity and Cardiac Function in Long-Term Breast Cancer Survivors: A Cross-Sectional Study.JACC. CardioOncology · 2022Article
- Combined Associations of Physical Activity and Particulate Matter With Subsequent Cardiovascular Disease Risk Among 5-Year Cancer Survivors.Journal of the American Heart Association · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
Abstract
purposeTo examine the association of physical activity among long-term breast cancer survivors on the occurrence of subsequent cardiovascular disease (CVD).
methodsWe investigated the risk of CVD among 39,775 breast cancer patients who were newly diagnosed in 2006 and survived until 2011 within the Korean National Health Insurance Service database. Patients were followed up from 5 years after breast cancer diagnosis to the date of CVD event, death, or December 31, 2018, whichever came earliest. Every 500 MET-mins/week correspond to 152, 125, and 62.5 min per week of light-, moderate-, and vigorous-intensity physical activity, respectively. Adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) for CVD were calculated using Cox proportional hazards regression by physical activity levels.
resultsCompared with those with physical activity of 0 MET-min/week, those with 1-499 (aHR 0.82, 95% CI 0.69-0.98), 500-999 (aHR 0.75, 95% CI 0.63-0.90), and ≥ 1,000 (aHR 0.76, 95% CI 0.63-0.93) MET-min/week of PA had lower risk of CVD. Higher levels of PA were associated with lower risk of stroke (p for trend = 0.016). The benefits of PA on obese and overweight breast cancer survivors were smaller than those in normal weight survivors. The frequency of moderate-to-vigorous physical activity (MVPA) showed a reverse J-curve association with CVD, and the best benefit occurred in the 3-4 times MVPA per week group (aHR 0.59, 95% CI 0.46-0.74).
conclusionsThe study showed that even small amounts of PA may be beneficial in potentially decreasing the risk of CVD, CHD, and stroke in breast cancer survivors. Our result will be useful to prescribe and delivery exercise among long-term breast cancer survivors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.