ArticleEuropean journal of nuclear medicine and molecular imaging2021
Spatially constrained kinetic modeling with dual reference tissues improves
Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Noninvasive Quantification of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026Article
- Patlak-PBNT: a simple population-based Patlak model to generate [EJNMMI physics · 2026Article
- Cerebral Amyloid Deposition WithHuman brain mapping · 2025Article
- Model selection for dynamic PET compartmental modelling ofEJNMMI research · 2025Article
- Brain tau PET-based identification and characterization of subpopulations in patients with Alzheimer's disease using deep learning-derived saliency maps.EJNMMI physics · 2025Article
- Exploring the nigrostriatal and digestive interplays in Parkinson's disease using dynamic total-body [European journal of nuclear medicine and molecular imaging · 2024Article
- Automated extraction of the arterial input function from brain images for parametric PET studies.EJNMMI research · 2024Article
- Kinetic analysis of cardiac dynamicHeliyon · 2024Article
- Comparison of parametric imaging and SUV imaging with [European journal of nuclear medicine and molecular imaging · 2024Article
- A review of the flortaucipir literature for positron emission tomography imaging of tau neurofibrillary tangles.Brain communications · 2024Review
- Motion correction and its impact on quantification in dynamic total-body 18F-fluorodeoxyglucose PET.EJNMMI physics · 2022Article
- Tracer-specific reference tissues selection improves detection ofHuman brain mapping · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeRecent studies have shown that standard compartmental models using plasma input or the cerebellum reference tissue input are generally not reliable for quantifying tau burden in dynamic
methodsParticipants were classified as either cognitively normal (CN) or cognitively impaired (CI) based on clinical assessment. T1-weighted structural MRI and 105-min dynamic
resultsThe percent coefficients of variation of R
conclusionUsing a spatially constrained kinetic model with dual reference tissues significantly improved quantification of relative perfusion and tau binding. Cerebellum and CS are the suggested reference tissues to estimate R
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