Evidence map›Paper›PMID 33599809›Full record

Trial reportPsychopharmacology2021

An interoceptive basis for alcohol priming effects.

Mateo Leganes-Fonteneau, Marsha E Bates, Evgeny G Vaschillo, Jennifer F Buckman

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Cardiovascular mechanisms of interoceptive awareness: Effects of resonance breathing.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mateo Leganes-FonteneauDepartment of Kinesiology and Health, Rutgers University, New Brunswick, NJ, USA. mateo.leganes@rutgers.edu.ORCID http://orcid.org/0000-0002-3299-9125
Marsha E BatesDepartment of Kinesiology and Health, Rutgers University, New Brunswick, NJ, USA. mebates@smithers.rutgers.edu.
Evgeny G VaschilloDepartment of Kinesiology and Health, Rutgers University, New Brunswick, NJ, USA.
Jennifer F BuckmanDepartment of Kinesiology and Health, Rutgers University, New Brunswick, NJ, USA.

Funding

Project IMPACT: In-the-Moment Protection from Automatic Capture by TriggersR01AA023667 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI BATES, MARSHA E., BUCKMAN, JENNIFER F. · 2015 to 2019
$2.7M
Deconstructing the temporal and multi-level influences of the baroreflex mechanism on alcohol use behaviorsK02AA025123 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI BUCKMAN, JENNIFER F. · 2017 to 2021
$762k
NIAAA NIH HHS K02 AA025123NIAAA NIH HHS K02AA025123NIAAA NIH HHS R01AA023667
6 · The paper itself

Abstract

rationaleAlcohol priming can modulate the value of rewards, as observed through the effects of acute alcohol administration on cue reactivity. However, little is known about the psychophysiological mechanisms driving these effects. Here, we examine how alcohol-induced changes in bodily states shape the development of implicit attentional biases and explicit cue reactivity.

objectivesTo characterize the interoceptive correlates of alcohol priming effects on alcohol attentional biases and cue reactivity.

methodsIn a two-session double-blind alcohol administration procedure, participants (n=31) were given a 0.4-g/kg dose of alcohol or a placebo drink. Cardiovascular responses were measured before and after alcohol administration to observe the effects of alcohol on viscero-afferent reactivity, as indexed through changes in heart rate variability (HRV) at or near 0.1 Hz (0.1-Hz HRV). Next, participants completed a modified flanker task to examine implicit alcohol attentional biases and provided subjective valence and arousal ratings of alcohol cues to examine explicit cue reactivity.

resultsWe found that changes in 0.1-Hz HRV after alcohol administration positively correlated with attentional biases, and negatively correlated with alcohol valence ratings; blood alcohol content was a null predictor.

conclusionsThis is novel evidence that suggests alcohol-induced changes in bodily states may mediate the occurrence of alcohol priming effects and highlights the potentially generative role of interoceptive mechanisms in alcohol-related behaviors. The differential patterns revealed by implicit biases and explicit response tendencies are considered within the context of the dissociation between wanting and liking.

Indexed as

AdultAlcohol DrinkingArousalAttentionAttentional BiasCuesDouble-Blind MethodEmotionsEthanolFemaleHeart RateHumansMaleYoung AdultEthanolAlcohol administrationAlcohol primingAttentional biasHeart rate variabilityInteroception

Identifiers

PMID33599809
PMCPMC7889700

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.