Evidence map›Paper›PMID 33599621›Full record

ArticleJournal of medical Internet research2021

Access to Technology and Preferences for an mHealth Intervention to Promote Medication Adherence in Pediatric Acute Lymphoblastic Leukemia: Approach Leveraging Behavior Change Techniques.

Mallorie B Heneghan, Tasmeen Hussain, Leonardo Barrera, Stephanie W Cai, Maureen Haugen, Elaine Morgan, Jenna Rossoff, Joanna Weinstein, Nobuko Hijiya, David Cella and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 6 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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  15. eHealth: A Survey of Architectures, Developments in mHealth, Security Concerns and Solutions.International journal of environmental research and public health · 2022
    Article
  16. How technology can improve communication and health outcomes in patients with advanced cancer: an integrative review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Mallorie B HeneghanDivision of Pediatric Hematology/Oncology, Department of Pediatrics, University of Utah, Salt Lake City, UT, United States.ORCID 0000-0001-9454-0857
Tasmeen HussainDivision of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.ORCID 0000-0003-4101-3687
Leonardo BarreraMary Ann & J. Milburn Smith Child Health Research, Outreach, and Advocacy Center, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.ORCID 0000-0001-9812-7883
Stephanie W CaiDepartment of Obstetrics & Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.ORCID 0000-0002-5617-2026
Maureen HaugenDivision of Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.ORCID 0000-0002-3251-9478
Elaine MorganDivision of Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.ORCID 0000-0003-2505-8885
Jenna RossoffDivision of Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.ORCID 0000-0003-0471-9883
Joanna WeinsteinDivision of Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.ORCID 0000-0003-0585-9669
Nobuko HijiyaDepartment of Pediatrics, Columbia University Medical Center, New York, NY, United States.ORCID 0000-0002-0199-054X
David CellaDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.ORCID 0000-0002-9881-4541
Sherif M BadawyDivision of Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.ORCID 0000-0002-4739-265X
Northwestern University · USLurie Children's Hospital · USColumbia University Irving Medical Center · USUniversity of Utah · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Northwestern University Patient-centered Intervention and Engagement TrainingK12HS023011 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CELLA, DAVID · 2014 to 2018
$3.7M
An mHealth Strategy to Improve Medication Adherence in Adolescents with Sickle Cell DiseaseK23HL150232 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI BADAWY, SHERIF MOHAMED · 2020 to 2024
$842k
AHRQ HHS K12 HS023011NCATS NIH HHS UL1 TR001422NHLBI NIH HHS K23 HL150232
6 · The paper itself

Abstract

backgroundSuboptimal adherence to 6-mercaptopurine (6-MP) is prevalent in pediatric acute lymphoblastic leukemia (ALL) and associated with increased risk of relapse. Rapid uptake of personal technology makes mobile health (mHealth) an attractive platform to promote adherence.

objectiveStudy objectives were to examine access to mobile technology and preferences for an mHealth intervention to improve medication adherence in pediatric ALL.

methodsA cross-sectional survey was administered in oncology clinic to parents of children with ALL as well as adolescents and young adults (AYAs) with ALL receiving maintenance chemotherapy.

resultsA total of 49 parents (median age [IQR] 39 [33-42] years; female 76% [37/49]) and 15 patients (median age [IQR] 17 [16-19]; male 80% [12/15]) participated. All parents and AYAs owned electronic tablets, smartphones, or both. Parents' most endorsed mHealth app features included a list of medications (71%, 35/49), information about 6-MP (71%, 35/49), refill reminders (71%, 35/49), and reminders to take 6-MP (71%, 35/49). AYAs' most endorsed features included refill reminders (73%, 11/15), reminders to take 6-MP (73%, 11/15), and tracking 6-MP (73%, 11/15).

conclusionsParents and AYAs reported ubiquitous access to mobile technology and strong interest in multiple adherence-specific mHealth app features. Parents and AYAs provided valuable insight into preferred features for a multifunctional behavioral intervention (mHealth app) to promote medication adherence in pediatric ALL.

Indexed as

Drug MonitoringAdolescentAdultBehavior TherapyChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleMobile ApplicationsPrecursor Cell Lymphoblastic Leukemia-LymphomaSmartphoneSurveys and QuestionnairesTechnologyTelemedicineacute lymphoblastic leukemiabehavior change techniquemedication adherencemHealthoral chemotherapypatient-centered

Identifiers

PMID33599621
PMCPMC7932843
OpenAlexW3119724614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.