Evidence map›Paper›PMID 33599613›Full record

ArticleeLife2021

Repressing

Qiuying Liu, Xiaoli Chen, Mariah K Novak, Shaojie Zhang, Wenqian Hu

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. RNA-Binding Protein Trim71 Controls Epicardial Cell Migration.Journal of cardiovascular development and disease · 2026
    Article
  2. Article
  3. Article
  4. CSDE1 stabilizes AGO2 in embryonic stem cells.Frontiers in molecular biosciences · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. A neural stem cell paradigm of pediatric hydrocephalus.Cerebral cortex (New York, N.Y. : 1991) · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Biomedicines · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qiuying LiuDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, United States.ORCID 0000-0002-1474-4487
Xiaoli ChenDepartment of Computer Science, University of Central Florida, Orlando, United States.
Mariah K NovakDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, United States.ORCID 0000-0003-1547-4738
Shaojie ZhangDepartment of Computer Science, University of Central Florida, Orlando, United States.ORCID 0000-0002-4051-5549
Wenqian HuDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, United States.ORCID 0000-0003-3577-3604
Mayo Clinic · USUniversity of Central Florida · US

Funding

Studies of mRNA translational regulations in erythropoiesisR01HL141112 · NHLBI · MAYO CLINIC ROCHESTER · PI HU, WENQIAN · 2018 to 2022
$2.0M
Molecular mechanistic studies of long “noncoding” RNAs in mammalian cell differentiationR01GM136869 · NIGMS · MAYO CLINIC ROCHESTER · PI HU, WENQIAN · 2021 to 2024
$1.4M
Studies of translational regulatory networks in macrophage-mediated inflammatory responsesR21AI146431 · NIAID · MAYO CLINIC ROCHESTER · PI HU, WENQIAN · 2019 to 2020
$441k
NHLBI NIH HHS R01 HL141112NIAID NIH HHS R21 AI146431NIGMS NIH HHS R01 GM136869
6 · The paper itself

Abstract

The regulation of stem cell fate is poorly understood. Genetic studies in

Indexed as

Protein BiosynthesisAnimalsArgonaute ProteinsCell LineEmbryo, MammalianEmbryonic Stem CellsMiceMicroRNAsPluripotent Stem CellsRNA, MessengerTranscription FactorsAgo2 protein, mouseArgonaute ProteinsLIN-41 protein, mouseMicroRNAsmirnlet7 microRNA, mouseRNA, MessengerTranscription Factorscell biologychromosomesgene expressionlet-7Lin41mousepluripotencyRNA-binding proteintranslational controlTrim71

Identifiers

PMID33599613
PMCPMC7906602
OpenAlexW3132018777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.