ArticleBiomaterials science2021
Combination strategies for antithrombotic biomaterials: an emerging trend towards hemocompatibility.
Article in Biomaterials science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Fabrication of Bioinspired Hydrogels Using Carboxyphenylboronic Acid-Grafted Polyethylenimine and Polyvinyl Alcohol for Potential Wound Dressing Applications.Biomimetics (Basel, Switzerland) · 2026Article
- Nano-engineering the titanium-tissue interface: a 15 year perspective on bio-functionalization and surface innovation.Nanoscale advances · 2026Review
- Spatiotemporal evaluation of antithrombotic performance for biomaterials through monitoring β-sheet conformation changes at the blood interface.Bioactive materials · 2026Article
- Antithrombotic Polymers: A Narrative Review on Current and Future Strategies for Their Design, Synthesis, and Application.International journal of molecular sciences · 2026Review
- Enhancing Hemocompatibility in ECMO Systems With a Fibrinolytic Interactive Coating: in Vitro Evaluation of Blood Clot Lysis Using a 3D Microfluidic Model.Macromolecular bioscience · 2025Article
- Antithrombotic coating with sheltered positive charges prevents contact activation by controlling factor XII-biointerface binding.Nature materials · 2025Article
- Surface Engineering for Endothelium-Mimicking Functions to Combat Infection and Thrombosis in Extracorporeal Life Support Technologies.Advanced healthcare materials · 2024Article
- Unravelling Surface Modification Strategies for Preventing Medical Device-Induced Thrombosis.Advanced healthcare materials · 2024Review
- Functionalization ofBioactive materials · 2023Article
- Derivatization of graphene oxide nanosheets with tunable nitric oxide release for antibacterial biomaterials.Journal of biomedical materials research. Part A · 2023Article
- Synthesis and Characterization of Nitric Oxide-Releasing Ampicillin as a Potential Strategy for Combatting Bacterial Biofilm Formation.ACS applied materials & interfaces · 2023Article
- Polyester urethane urea (PEUU) functionalization for enhanced anti-thrombotic performance: advancing regenerative cardiovascular devices through innovative surface modifications.Frontiers in bioengineering and biotechnology · 2023Article
- Strategies for surface coatings of implantable cardiac medical devices.Frontiers in bioengineering and biotechnology · 2023Review
- Thrombin and Factor Xa Hydrolysis of Chromogenic Substrates in the Presence of Sulfated Derivatives of Galactomannan and Galactoglucomannan Natural Gels.Pharmaceutics · 2022Article
- Mechanisms for Reduced Fibrin Clot Formation on Liquid-Infused Surfaces.Advanced healthcare materials · 2022Article
- Bio-inspired hemocompatible surface modifications for biomedical applications.Progress in materials science · 2022Article
- Molecular Characterization and Biocompatibility of Exopolysaccharide Produced by Moderately Halophilic BacteriumPolymers · 2022Article
- Recent Developments in Multifunctional Antimicrobial Surfaces and Applications toward Advanced Nitric Oxide-Based Biomaterials.ACS materials Au · 2022Review
- Nitric Oxide-Releasing Lock Solution for the Prevention of Catheter-Related Infection and Thrombosis.ACS applied bio materials · 2022Article
- Surface Texturing and Combinatorial Approaches to Improve Biocompatibility of Implanted Biomaterials.Frontiers in physics · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Surface-induced thrombosis is a frequent, critical issue for blood-contacting medical devices that poses a serious threat to patient safety and device functionality. Antithrombotic material design strategies including the immobilization of anticoagulants, alterations in surface chemistries and morphology, and the release of antithrombotic compounds have made great strides in the field with the ultimate goal of circumventing the need for systemic anticoagulation, but have yet to achieve the same hemocompatibility as the native endothelium. Given that the endothelium achieves this state through the use of many mechanisms of action, there is a rising trend in combining these established design strategies for improved antithrombotic actions. Here, we describe this emerging paradigm, highlighting the apparent advantages of multiple antithrombotic mechanisms of action and discussing the demonstrated potential of this new direction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.