Evidence map›Paper›PMID 33598933›Full record

ArticleClinical cardiology2021

The characteristics and efficacy of catheter ablation of focal atrial tachycardia arising from an epicardial site.

Teppei Yamamoto, Yu-Ki Iwasaki, Yuhi Fujimoto, Eiichiro Oka, Hiroshi Hayashi, Hiroshige Murata, Kenji Yodogawa, Meiso Hayashi, Osamu Igawa, Wataru Shimizu

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Teppei YamamotoDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.ORCID https://orcid.org/0000-0002-2432-9156
Yu-Ki IwasakiDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Yuhi FujimotoDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Eiichiro OkaDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Hiroshi HayashiDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.ORCID https://orcid.org/0000-0001-8202-9867
Hiroshige MurataDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Kenji YodogawaDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9978-7402
Meiso HayashiDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Osamu IgawaDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Wataru ShimizuDepartment of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Nippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough epicardial structures around the atrium such as adipose tissue possess arrhythmogenicity, little is known about atrial tachycardias (ATs) originating from epicardial sites (Epi-ATs). This study aimed to elucidate the prevalence, characteristics, and outcome after radiofrequency catheter ablation (RFCA) of Epi-ATs and to reveal the association between Epi-ATs and the epicardial structures.

methodsThe electrocardiographic, electrophysiologic, and anatomical properties and results of RFCA were analyzed in 42 patients with a total of 49 ectopic ATs.

resultsSix Epi-ATs (12%) were observed in six patients (14%). Four of six were respiratory cycle-dependent ATs and one was a swallowing-induced AT. The Epi-AT origins were adjacent to a pulmonary vein (five cases) and vein of Marshall (one case). A Valsalva maneuver or atropine infusion to define the arrhythmia mechanism affected the appearance of the Epi-ATs. The congruity rate between epicardial adipose tissue and the AT origin was significantly higher (100% vs. 44%, p = .045), and the epicardial adipose tissue volume of the atrium was significantly larger (104.1 vs. 64.6 ml, p = .04) in the Epi-AT group. Endocardial RFCA targeting the AT foci resulted in acute success in five of five cases. However, electrical isolation including of the AT foci resulted in acute failures (two of three cases) or a recurrence (one of one case).

conclusionsSix Epi-ATs were associated with thoracic veins and epicardial arrhythmogenic structures. The main cause provoking the Epi-ATs was associated with autonomic nerve activity.

Indexed as

Atrial FibrillationCatheter AblationPulmonary VeinsTachycardia, SupraventricularHeart AtriaHumansTreatment Outcomeablationatrial tachycardiaautonomic nerve activityepicardial adipose tissuerespiratoryswallowing

Identifiers

PMID33598933
PMCPMC8027578
OpenAlexW3129578983

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.