Evidence map›Paper›PMID 33598826›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2021

Predictors of renal replacement therapy in patients with continuous flow left ventricular assist devices.

Umang Parikh, Harveen Lamba, Muhammad Ajmal, Justin Vincent, Carl Walther, Alexis Shafii, Ajith Nair, Andrew Civitello, Kenneth Liao, Subhasis Chatterjee

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Left Ventricular Assist Devices and Renal Ramifications.Journal of the American Heart Association · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Umang ParikhDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Harveen LambaDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA. harveen.lamba@bcm.edu.ORCID http://orcid.org/0000-0002-0611-1030
Muhammad AjmalDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Justin VincentDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Carl WaltherDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Alexis ShafiiDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Ajith NairDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Andrew CivitelloDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Kenneth LiaoDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Subhasis ChatterjeeDivision of Cardiothoracic Transplantation and Circulatory Support and Division of Cardiology, Baylor College of Medicine, 6720 Bertner Ave, Houston, TX, 77030, USA.
Baylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal replacement therapy (RRT) after continuous flow left ventricular assist device (CF-LVAD) implantation significantly affects patients' quality of life and survival. To identify preoperative prognostic markers in patients requiring RRT after CF-LVAD implantation, we retrospectively reviewed data from patients who underwent implantation of a CF-LVAD at our institution during 2012-2017. Patients who required preoperative RRT were excluded. Preoperative and operative characteristics, as well as survival and adverse events, were compared between 74 (22.2%) patients requiring any duration of postoperative RRT and 259 (77.8%) not requiring RRT. Patients requiring RRT experienced more postoperative complications than patients who did not, including respiratory failure necessitating tracheostomy (35.7% vs 2.5%, p < 0.001), reoperation for bleeding (34.3% vs 11.7%, p < 0.001), and right heart failure necessitating perioperative mechanical circulatory support (32.4% vs 6.9%, p < 0.001). Patients requiring postoperative RRT also had poorer survival at 30 days (74.7% vs 98.8%), 6 months (48.2% vs 95.1%), and 12 months (45.3% vs 90.2%) (p < 0.001). Significant predictors of RRT after CF-LVAD implantation included urine proteinuria (odds ratio [OR] 3.6, 95% confidence interval [CI] [1.7-7.6], p = 0.001), estimated glomerular filtration rate < 45 mL/min/1.73 m

Indexed as

Heart-Assist DevicesRenal Replacement TherapyAdultEquipment DesignFemaleHeart FailureHumansMaleMiddle AgedPrognosisQuality of LifeRenal InsufficiencyRetrospective StudiesTime FactorsVentricular Dysfunction, LeftBiomarkerCardiorenal syndromeDialysisLVADRenal insufficiency

Identifiers

PMID33598826
OpenAlexW3133262461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.