Evidence map›Paper›PMID 33598722›Full record

SynthesisWorld journal of surgery2021

Revisiting Amyand's Hernia: A 20-Year Systematic Review.

Dimitrios K Manatakis, Nikolaos Tasis, Maria Ioanna Antonopoulou, Petros Anagnostopoulos, Vasileios Acheimastos, Dimitrios Papageorgiou, Evangelos Fradelos, Menelaos Zoulamoglou, Christos Agalianos, John Tsiaoussis and 1 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
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  13. Review
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  15. De Garengeot Hernia with Acute Gangrenous Appendicitis Case Report.Clinical practice and cases in emergency medicine · 2025
    Article
  16. Article
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  18. Article
  19. Article
  20. Intraoperative diagnosis of Amyand's hernia, a case report.International journal of surgery case reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Dimitrios K ManatakisSecond Department of Surgery, Athens Naval and Veterans Hospital, Eptanisou 18, Agia Varvara, Athens, Greece.
Nikolaos TasisSecond Department of Surgery, Athens Naval and Veterans Hospital, Eptanisou 18, Agia Varvara, Athens, Greece. tasisnikolaos@gmail.com.ORCID http://orcid.org/0000-0002-8523-6316
Maria Ioanna AntonopoulouSecond Department of Surgery, Athens Naval and Veterans Hospital, Eptanisou 18, Agia Varvara, Athens, Greece.
Petros AnagnostopoulosSecond Department of Surgery, Athens Naval and Veterans Hospital, Eptanisou 18, Agia Varvara, Athens, Greece.
Vasileios AcheimastosSecond Department of Surgery, Athens Naval and Veterans Hospital, Eptanisou 18, Agia Varvara, Athens, Greece.
Dimitrios PapageorgiouFirst Department of Surgery, Athens Naval and Veterans Hospital, Athens, Greece.
Evangelos FradelosFirst Department of Surgery, Athens Naval and Veterans Hospital, Athens, Greece.
Menelaos ZoulamoglouFirst Department of Surgery, Athens Naval and Veterans Hospital, Athens, Greece.
Christos AgalianosSecond Department of Surgery, Athens Naval and Veterans Hospital, Eptanisou 18, Agia Varvara, Athens, Greece.
John TsiaoussisLaboratory of Anatomy, Histology and Embryology, Medical School, University of Crete, Heraklion, Crete, Greece.
Evaghelos XynosCreta Interclinic Hospital, Heraklion, Crete, Greece.
Athens Naval & Veterans Hospital · GRUniversity Hospital of Heraklion · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeProtrusion of the appendix within an inguinal hernia is termed an Amyand's hernia. A systematic review of case reports and case series of Amyand's hernia was performed, with emphasis on surgical decision-making.

methodsThe English literature (2000-2019) was reviewed, using PubMed and Embase, combining the terms "hernia", "inguinal", "appendix", "appendicitis" and "Amyand". Overall, 231 studies were included, describing 442 patients.

resultsMean age of patients was 34 ± 32 years (adults 57.5%, children 42.5%). 91% were males, while a left-sided Amyand's hernia was observed in 9.5%. Of 156 elective hernia repairs, 38.5% underwent appendectomy and 61.5% simple reduction of the appendix. 88% of the adult patients had a mesh repair, without complications. Of 281 acute cases, hernial complications (76%) and acute appendicitis (12%) were the most common preoperative surgical indications. Appendectomy was performed in 79%, more extensive operations in 8% and simple reduction in 13% of cases. A mesh was used in 19% of adult patients following any type of resection and in 81% following reduction of the appendix. Among acute cases, mortality was 1.8% and morbidity 9.2%. Surgical site infections were observed in 3.6%, all of which in patients without mesh implantation.

conclusionIn elective Amyand's hernia cases, appendectomy may be considered in certain patients, provided faecal spillage is avoided, to prevent mesh infection. In cases of appendicitis, prosthetic mesh may be used, if the surgical field is relatively clean, whereas endogenous tissue repairs are preferred in cases of heavy contamination.

Indexed as

AppendicitisAppendixHernia, InguinalAdolescentAdultAgedAppendectomyChildChild, PreschoolHerniorrhaphyHumansMaleMiddle AgedYoung Adult

Identifiers

PMID33598722
OpenAlexW3131260812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.