Evidence map›Paper›PMID 33598639›Full record

ArticlemicroPublication biology2021

Actin polymerization is not required for the fast block to polyspermy in the African clawed frog,

Maiwase Tembo, Monica L Sauer, Bennett W Wisner, David O Beleny, Marc A Napolitano, Anne E Carlson

Abstract read
In one paragraph

Article in microPublication biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maiwase TemboDepartment of Biological Sciences, University of Pittsburgh.
Monica L SauerDepartment of Biological Sciences, University of Pittsburgh.
Bennett W WisnerDepartment of Biological Sciences, University of Pittsburgh.
David O BelenyDepartment of Biological Sciences, University of Pittsburgh.
Marc A NapolitanoDepartment of Biological Sciences, University of Pittsburgh.
Anne E CarlsonDepartment of Biological Sciences, University of Pittsburgh.

Funding

Signaling Mechanisms of TMEM16a RegulationR01GM125638 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARLSON, ANNE E · 2018 to 2022
$1.6M
Signaling Mechanisms of Polyspermy BlockR00HD069410 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARLSON, ANNE E · 2014 to 2016
$730k
NICHD NIH HHS R00 HD069410
6 · The paper itself

Abstract

Fertilization of an egg by multiple sperm presents one of the earliest and most prevalent obstacles to successful reproduction. Eggs employ multiple mechanisms to prevent sperm entry into the nascent zygote. The fast block to polyspermy uses a depolarization to inhibit sperm entry. For some external fertilizers, fertilization and the fast block require actin polymerization. Here we explored whether the fast block to polyspermy in the external fertilizer,

Identifiers

PMID33598639
PMCPMC7876547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.