Evidence map›Paper›PMID 33598506›Full record

ArticleOptica2019

Optical trapping assisted detection rate enhancement of single molecules on a nanopore optofluidic chip.

M Rahman, M Harrington, M A Stott, Y Li, M J N Sampad, T D Yuzvinsky, A R Hawkins, H Schmidt

Abstract read
In one paragraph

Article in Optica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M RahmanSchool of Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.
M HarringtonSchool of Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.
M A StottECEn Department, Brigham Young University, 450 Engineering Building, Provo, Utah 84602, USA.
Y LiSchool of Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.
M J N SampadSchool of Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.
T D YuzvinskySchool of Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.
A R HawkinsECEn Department, Brigham Young University, 450 Engineering Building, Provo, Utah 84602, USA.
H SchmidtSchool of Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.

Funding

Nanopore-based multi-target analysis of Zika virus infectionR01EB028608 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SCHMIDT, HOLGER · 2019 to 2022
$2.7M
NIBIB NIH HHS R01 EB028608
6 · The paper itself

Abstract

We use optical trapping to deliver molecular targets to the vicinity of a nanopore for high-throughput single molecule analysis on an optofluidic chip. DNA detection rates increase over 80× to enable detection at attomolar concentrations.

Identifiers

PMID33598506
PMCPMC7885897

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.