Evidence map›Paper›PMID 33598503›Full record

ReviewOpen forum infectious diseases2021

Meta-analysis of Clinical Outcomes Using Ceftazidime/Avibactam, Ceftolozane/Tazobactam, and Meropenem/Vaborbactam for the Treatment of Multidrug-Resistant Gram-Negative Infections.

Geneva M Wilson, Margaret Fitzpatrick, Kyle Walding, Beverly Gonzalez, Marin L Schweizer, Katie J Suda, Charlesnika T Evans

Open access · goldAbstract readReview
In one paragraph

Review in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The importance of monitoring a new antibiotic: ceftazidime/avibactam usage and resistance experience from England, 2016 to 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  4. Guidelines for Antibiotics Prescription in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Frontiers in antibiotics · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Treatment for carbapenem-resistant Enterobacterales infections: recent advances and future directions.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Geneva M WilsonCenter of Innovation for Complex Chronic Healthcare (CINCCH), Edward Hines Jr. Veterans Affairs Hospital, Hines, Illinois, USA.ORCID 0000-0002-3850-7689
Margaret FitzpatrickCenter of Innovation for Complex Chronic Healthcare (CINCCH), Edward Hines Jr. Veterans Affairs Hospital, Hines, Illinois, USA.
Kyle WaldingLoyola Medical Center, Maywood, Illinois, USA.
Beverly GonzalezCenter of Innovation for Complex Chronic Healthcare (CINCCH), Edward Hines Jr. Veterans Affairs Hospital, Hines, Illinois, USA.
Marin L SchweizerCollege of Public Health, University of Iowa, Iowa City, Iowa, USA.
Katie J SudaCenter for Health Equity Research and Promotion, VA Pittsburgh Heath Care System, Pittsburgh, Pennsylvania, USA.
Charlesnika T EvansCenter of Innovation for Complex Chronic Healthcare (CINCCH), Edward Hines Jr. Veterans Affairs Hospital, Hines, Illinois, USA.
Edward Hines, Jr. VA Hospital · USLoyola University Medical Center · USNorthwestern University · USUniversity of Iowa · USUniversity of Pittsburgh · US

Funding

Effectiveness of Treatment and Outcomes for Veterans Infected with Resistant Gram-negative Organisms.I01HX002169 · VA · EDWARD HINES JR VA HOSPITAL · PI EVANS, CHARLESNIKA T · 2018 to 2021
–
HSR&D Research Career Scientist AwardIK6HX003156 · VA · EDWARD HINES JR VA HOSPITAL · PI EVANS, CHARLESNIKA T · 2020 to 2025
–
HSRD VA I01 HX002169HSRD VA IK6 HX003156
6 · The paper itself

Abstract

Ceftolozane-tazobactam (C/T), ceftazidime-avibactam (C/A), and meropenem/vaborbactam (M/V) are new beta-lactam/beta-lactamase combination antibiotics commonly used to treat multidrug-resistant

Indexed as

antimicrobial resistanceepidemiologymeta-analysismultidrug-resistant infections

Identifiers

PMID33598503
PMCPMC7875326
OpenAlexW3118913333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.