Evidence map›Paper›PMID 33598431›Full record

ArticleFrontiers in oncology2020

Hemicolectomy Does Not Provide Survival Benefit for Right-Sided Mucinous Colon Adenocarcinoma.

Jia Huang, Qiulin Huang, Rong Tang, Guodong Chen, Yiwei Zhang, Rongfang He, Xuyu Zu, Kai Fu, Xiuda Peng, Shuai Xiao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jia HuangInstitute of Clinical Medicine, the First Affiliated Hospital, University of South China, Hengyang, China.
Qiulin HuangDepartment of Gastrointestinal Surgery, the First Affiliated Hospital, University of South China, Hengyang, China.
Rong TangDepartment of Gastrointestinal Surgery, the First Affiliated Hospital, University of South China, Hengyang, China.
Guodong ChenDepartment of Surgery, the First Affiliated Hospital, University of South China, Hengyang, China.
Yiwei ZhangDepartment of Surgery, the First Affiliated Hospital, University of South China, Hengyang, China.
Rongfang HeDepartment of Pathology, the First Affiliated Hospital, Hengyang, China.
Xuyu ZuInstitute of Clinical Medicine, the First Affiliated Hospital, University of South China, Hengyang, China.
Kai FuInstitute of Molecular Precision Medicine and Hunan Key Laboratory of Molecular Precision Medicine, Xiangya Hospital, Central South University, Changsha, China.
Xiuda PengDepartment of Surgery, the Second Affiliated Hospital, University of South China, Hengyang, China.
Shuai XiaoInstitute of Clinical Medicine, the First Affiliated Hospital, University of South China, Hengyang, China.
University of South China · CNFirst Affiliated Hospital of University of South China · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe extent of bowel resection is widely debated in colon cancer surgery. Right hemicolectomy (RHC) and partial colectomy (PC) are the most common operation options for right-sided colon cancer (RCC). However, there are still no treatment guidelines or published studies to guide surgical options for mucinous adenocarcinoma (MAC) of RCC.

methodsPatients with MAC and non-specific adenocarcinoma (AC) of RCC who underwent RHC and PC from 2010 to 2015 in the Surveillance, Epidemiology, and End Results (SEER) database were retrieved. The general characteristics and survival were compared and analyzed.

resultsA total of 27,910 RCC patients were enrolled in this study, among them 3,413 were MAC. The results showed that race, carcinoembryonic antigen (CEA) level, perineural invasion (PNI), tumor size, tumor location, TNM stage, liver metastasis, chemotherapy were significantly different between MAC and AC groups. The MAC group had similar dissected lymph nodes, but more positive lymph nodes than the AC group. The overall survival (OS) of the MAC group was poorer than that of the AC group, but cancer-specific survival (CSS) was similar between the two groups. The RHC subgroup of the MAC group had more patients of age ≤60 years, larger tumor size, cecum/ascending colon location and dissected lymph nodes than the PC subgroup, but similar positive lymph nodes, perioperative mortality, OS and CSS as the PC subgroup. Moreover, the univariate and multivariable analyses for the survival of RCC patients with MAC showed that RHC might not be a superior predictor for OS and CSS compared with PC.

conclusionsRHC could not dissect more positive lymph nodes or provide long-term survival benefits for RCC patients with MAC compared with PC. This study could provide some evidence for surgery treatment selection for MAC of RCC, which has important clinical value in individual management of colon cancer patients.

Indexed as

mucinous adenocarcinomapartial colectomyright hemicolectomyright-sided colon cancersurvival

Identifiers

PMID33598431
PMCPMC7882730
OpenAlexW3128131192

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.