Evidence map›Paper›PMID 33598395›Full record

ArticleJournal of oral biology and craniofacial research

Incidence OF HPV and EBV in oral cancer and their clinico-pathological correlation- a pilot study of 108 cases.

Shahi Vanshika, Agarwal Preeti, Qayoom Sumaira, Kumar Vijay, Tewari Shikha, Raghuvanshi Shivanjali, Singh Uma Shankar, Goel Madhu Mati

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Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Role of epigenetics in OSCC: an understanding above genetics.Medical oncology (Northwood, London, England) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shahi VanshikaDepartment of Pathology, King George's Medical University, Lucknow, UP, India.
Agarwal PreetiDepartment of Pathology, King George's Medical University, Lucknow, UP, India.
Qayoom SumairaDepartment of Pathology, King George's Medical University, Lucknow, UP, India.
Kumar VijayDepartment of Surgical Oncology, King George's Medical University, Lucknow, UP, India.
Tewari ShikhaDepartment of Laboratory Medicine and Pathology, Medanta Hospital, Lucknow, UP, India.
Raghuvanshi ShivanjaliDepartment of Pathology, King George's Medical University, Lucknow, UP, India.
Singh Uma ShankarDepartment of Pathology, King George's Medical University, Lucknow, UP, India.
Goel Madhu MatiDepartment of Laboratory Medicine and Pathology, Medanta Hospital, Lucknow, UP, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOut of all non-communicable diseases, cancer is the leading cause of death in the 21st century. Oral cancer ranks in top ten cancers in the world and oncogenic viruses contribute to its development and are a major preventable risk factor for it. MATERIAL AND

methodsIn the present study we intend to find the incidence of HPV and EBV by PCR in 108 sporadic oral cancer patients and study the clinico-pathological variables in agreement to their presence or absence.

resultsWe found that the incidence of EBV in oral cancer is much higher (30/108; 27.8%) than HPV 16 (14/108; 13%) and, a complete absence of HPV 18 (0/108) was reported by real time PCR. Co-infection by EBV and HPV was reported in 5.6% cases (6/108). However, on comparing this data with the corresponding clinico-pathological cofactors (age, gender, grade of tumour, tumour size, nodal status, metastasis, DOI, TIL, ENE) it was found that there was no statistical significance between the two.

conclusionHence, we conclude that these oncogenic viruses are independent cofactors to oral cancer development and none of the clinico-morphologic variable is associated with the viral etiology.

Indexed as

EBVHPVOncogenic virusesOral cancerReal time PCR

Identifiers

PMID33598395
PMCPMC7868717

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