ArticleGlobal heart2021
Disparities in Cardiovascular Research Output and Disease Outcomes among High-, Middle- and Low-Income Countries - An Analysis of Global Cardiovascular Publications over the Last Decade (2008-2017).
Article in Global heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Pooled it
- Artificial intelligence in the risk prediction models of cardiovascular disease and development of an independent validation screening tool: a systematic review.BMC medicine · 2024Pooled it
- Risk Factors for Cardiovascular Disease: Epidemiology, Screening, Prevention, and Therapeutic Interventions.MedComm · 2026Review
- Folate and global health review series, part 3: syntheses on cardiovascular, cerebrovascular, and metabolic diseases.Journal of global health · 2026Review
- The Urgent Need to Harness Public Health Interventions to Tackle the Burden of Cardiovascular Diseases in Africa: Opportunities, Challenges, and Recommendations.Health science reports · 2026Article
- Major adverse cardiovascular events, morbidity, and mortality, among people living with and without HIV in two northern Uganda hospitals.BMC infectious diseases · 2026Article
- Causal Relationships Between Major Depressive Disorder and Coronary Artery Disease Across Diverse Populations: A Bidirectional Mendelian Randomisation Study.Tropical medicine & international health : TM & IH · 2026Article
- Converting From Paper to Electronic Charting for a Nurse-Led Programme Serving High-Risk Postpartum Women and Infants in Malawi.Nursing open · 2025Article
- Emphasizing the role of cardiothoracic surgeons within the global health context: a call to action.Annals of medicine and surgery (2012) · 2025Review
- A century of cardiac rehabilitation research: Bibliometric review of publication history, keyword trends, and citations.NPJ cardiovascular health · 2025Article
- Two-Year Follow-Up of Patients With Atrial Fibrillation Receiving Edoxaban in Routine Clinical Practice: Results From the Global ETNA-AF Program.Clinical cardiology · 2025Article
- Awareness, knowledge, and attitude towards basic life support among healthcare professional students in Bangladesh.PLOS global public health · 2025Article
- Optimising Access to Care for Patients with Heart and Kidney Diseases: A World Heart Federation and International Society of Nephrology White Paper.Global heart · 2025Review
- Building Scientific Writing and Publication Capacity of New Authors from Low- and Middle-Income Countries: A Multicomponent Global Collaboration Model.Global heart · 2025Article
- Preventing premature cardiovascular mortality: the role of lifestyle interventions and pharmacotherapy-a narrative review.Frontiers in cardiovascular medicine · 2025Review
- Towards constructing a generalized structural 3D breathing human lung model based on experimental volumes, pressures, and strains.PLoS computational biology · 2025Article
- Precision cardiovascular medicine: shifting the innovation paradigm.Frontiers in science · 2025Article
- Equitable Global Representation in Cardiovascular Guidelines and Clinical Trials: Lacunae Remain.JACC. Advances · 2024Article
- Advancing Understanding and Addressing Disparities in Cardiomyopathy Care in Southern Africa.JACC. Advances · 2024Article
- Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians - An Indo-Kyrgyz cardiometabolic study.Journal of family medicine and primary care · 2024Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 4 countries.
Funding
Abstract
Background: Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. Health research is crucial to managing disease burden. Previous work has highlighted marked discrepancies in research output and disease burden between high-income countries (HICs) and low- and lower-middle-income countries (LI-LMICs) and there is little data to understand whether this gap has bridged in recent years. We conducted a global, country level bibliometric analysis of CVD publications with respect to trends in disease burden and county development indicators. Methods: A search filter with a precision and recall of 0.92 and 0.91 respectively was developed to extract cardiovascular publications from the Web of Science (WOS) for the years 2008-2017. Data for disease burden and country development indicators were extracted from the Global Burden of Disease and the World Bank database respectively. Results: Our search revealed 847,708 CVD publications for the period 2008-17, with a 43.4% increase over the decade. HICs contributed 81.1% of the global CVD research output and accounted for 8.1% and 8.5% of global CVD DALY losses deaths respectively. LI-LMICs contributed 2.8% of the total output and accounted for 59.5% and 57.1% global CVD DALY losses and death rates. Conclusions: A glaring disparity in research output and disease burden persists. While LI-LMICs contribute to the majority of DALYs and mortality from CVD globally, their contribution to research output remains the lowest. These data call on national health budgets and international funding support to allocate funds to strengthen research capacity and translational research to impact CVD burden in LI-LMICs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.