Evidence map›Paper›PMID 33598252›Full record

ArticleClinical case reports2021

The curious case of HLA-DR-positive APL.

Kanta Devi, Natasha Ali

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Acute promyelocytic leukemia with secondary myelofibrosis and positive CD34 expression.International journal of clinical and experimental pathology · 2026
    Article
  2. The curious case of HLA-DR-positive APL.Clinical case reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kanta DeviDepartment of Oncology Aga Khan University Karachi Pakistan.
Natasha AliDepartment of Pathology and Laboratory Medicine/Oncology Aga Khan University Karachi Pakistan.ORCID https://orcid.org/0000-0003-4990-330X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The triad of weak/absent CD34, negative HLA-DR expression, and positivity to CD117 is pathognomonic for the diagnosis of acute promyelocytic leukemia. However, in rare cases, strong positivity to HLD-DR and CD34 may be noted.

Indexed as

APLCD34 positivityHLA‐DR positivityPML‐RARα

Identifiers

PMID33598252
PMCPMC7869374

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.