Evidence map›Paper›PMID 33598019›Full record

ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2020

Post-stroke infection in acute ischemic stroke patients treated with mechanical thrombectomy does not affect long-term outcome.

Klaudia Nowak, Justyna Derbisz, Jan Pęksa, Bartłomiej Łasocha, Paweł Brzegowy, Joanna Slowik, Paweł Wrona, Roman Pulyk, Tadeusz Popiela, Agnieszka Slowik

Open access · goldAbstract read
In one paragraph

Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Long-term outcomes of mechanical thrombectomy in acute ischaemic stroke patients with concomitant malignancy.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Klaudia NowakDepartment of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Justyna DerbiszDepartment of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Jan PęksaDepartment of Cardiology, Interventional Cardiology and Hypertension, University Hospital, Krakow, Poland.
Bartłomiej ŁasochaDepartment of Radiology, University Hospital, Krakow, Poland.
Paweł BrzegowyDepartment of Radiology, University Hospital, Krakow, Poland.
Joanna SlowikDepartment of Dental Prophylaxis and Experimental Dentistry, Jagiellonian University Medical College, Krakow, Poland.
Paweł WronaDepartment of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Roman PulykDepartment of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Tadeusz PopielaDepartment of Radiology, University Hospital, Krakow, Poland.
Agnieszka SlowikDepartment of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Jagiellonian University · PLKrakow Cardiovascular Research Institute · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe impact of an infection that requires antibiotic treatment (IRAT) after an acute ischemic stroke (AIS) treated with mechanical thrombectomy (MT) remains unclear.

aimHere, we studied the prevalence and the profile of IRAT in patients with AIS treated with MT, aiming to identify predictive factors and prognostic implications at 90 days after stroke. MATERIAL AND

methodsWe analyzed parameters available within 24 h after AIS including demographics, risk factors, National Institutes of Health Stroke Scale (NIHSS) upon admission and 24 h later, hemorrhagic transformation (HT) on computed tomography, and several clinical and biochemical markers. The outcome measures were the modified Rankin Scale (mRS) 0-2 and 90 days post-stroke mortality.

resultsWe included 291 patients; in 184 (63.2%) patients MT was preceded by intravenous thrombolysis (IVT), and 83 (28.5%) patients developed IRAT. Multivariate analysis showed that male sex and hemorrhagic transformation on CT taken 24 h after stroke increased the risk of IRAT. We found that younger age, male sex, lower delta NIHSS, shorter time from stroke onset to groin puncture, better recanalization and a lack of hemorrhagic transformation on CT taken 24 h after stroke favorably affected outcome at day 90. Multivariate analysis showed that older age, higher delta NIHSS, unknown stroke etiology and lack of treatment with IVT were independent predictors of death up to day 90. Infection that required antibiotic treatment did not enter in the models for the studied outcome measures.

conclusionsIn AIS patients treated with MT, IRAT is not an independent factor that affects favorable outcome or mortality 90 days after stroke.

Indexed as

acute ischemic strokeantibiotic therapyinfectionslong-term outcomemechanical thrombectomymortality

Identifiers

PMID33598019
PMCPMC7863840
OpenAlexW3128973092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.