Evidence map›Paper›PMID 33597887›Full record

ArticleFrontiers in pharmacology2020

Curcumin Regulated the Homeostasis of Memory T Cell and Ameliorated Dextran Sulfate Sodium-Induced Experimental Colitis.

You-Bao Zhong, Zeng-Ping Kang, Bu-Gao Zhou, Hai-Yan Wang, Jian Long, Wen Zhou, Hai-Mei Zhao, Duan-Yong Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  9. Curcumin alleviates experimental colitisWorld journal of gastroenterology · 2022
    Article
  10. Review
  11. Article
  12. Article
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  14. Article
  15. Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases.International journal of molecular sciences · 2021
    Review
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

You-Bao ZhongDepartment of Postgraduate, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Zeng-Ping KangDepartment of Postgraduate, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Bu-Gao ZhouFormula-Pattern Research Center of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Hai-Yan WangFormula-Pattern Research Center of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Jian LongDepartment of Postgraduate, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Wen ZhouScience and Technology College, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Hai-Mei ZhaoCollege of Traditional Chinese Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Duan-Yong LiuFormula-Pattern Research Center of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Jiangxi University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune memory is protective against reinvasion by pathogens in the homeostatic state, while immune memory disorders can cause autoimmune disease, including inflammatory bowel disease. Curcumin is a natural compound shown to be effective against human inflammatory bowel disease and experimental colitis, but the underlying mechanism is unclear. Here, experimental colitis was induced by dextran sulfate sodium (DSS) in this study. Significant changes in the percentages of naïve, central memory T (TCM), and effector memory (TEM) cells and their CD4

Indexed as

curcuminexperimental colitisJAK1/STAT5 signaling pathwaymechanism of actionmemory T cells

Identifiers

PMID33597887
PMCPMC7882737
OpenAlexW3128917534

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.