ReviewFrontiers in molecular neuroscience2020
The Structure and Function of Ionotropic Receptors in
Review in Frontiers in molecular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Functional conservation of IR75q.2 in the recognition of volatile acids and aldehydes in two Spodoptera species.Crop health · 2026Article
- Semiochemical-Mediated Host-Searching and Biological Control Potential ofPlants (Basel, Switzerland) · 2026Review
- IR25a-like Receptors are Required for Olfactory Detection of Plant Volatiles in the Carmine Spider Mite.Journal of chemical ecology · 2026Article
- Article
- Transposable elements contribute to the evolution of host shift-related genes in cactophilicGenome research · 2026Article
- Chemical Composition Matters! The Role of Nepetalactone Isomers in Tick Repellency.Journal of chemical ecology · 2026Article
- Genome-Wide Characterization of Four Gastropod Species Ionotropic Receptors Reveals Diet-Linked Evolutionary Patterns of Functional Divergence.Animals : an open access journal from MDPI · 2026Article
- Review
- Gal4 drivers of the geosmin receptor Or56a exhibit ectopic expression in the labral sense organ of Drosophila.Scientific reports · 2025Article
- Shifts in bee diet breadths are associated with gene gains and losses and positive selection across olfactory receptors.G3 (Bethesda, Md.) · 2025Article
- Insight into molecular and neural mechanisms of general anesthesia from the invertebrate modelZoological research · 2025Review
- De novo genome assembly, annotation, and characterization of chemosensory genes in the camel ked (Hippobosca camelina).BMC genomics · 2025Article
- Monoacylglycerol acyltransferase maintains ionotropic receptor expression for cool temperature sensing and avoidance in Drosophila.Communications biology · 2025Article
- An enteric neuron-expressed variant ionotropic receptor detects ingested salts to regulate salt stress resistance.bioRxiv : the preprint server for biology · 2025Article
- Deregulated ion channels contribute to RHOBTB2-associated developmental and epileptic encephalopathy.Human molecular genetics · 2025Article
- Opponent coding mechanisms in Drosophila taste neurons.Chemical senses · 2025Review
- Amino acids activate parallel chemosensory pathways in Drosophila.Chemical senses · 2025Article
- The conserved IR75 subfamily mediates carboxylic acid detection in insects of public health and agricultural importance.Journal of insect science (Online) · 2025Review
- The expansion and loss of specific olfactory genes in relatives of parasitic lice, the stored-product psocids (Psocodea: Liposcelididae).BMC genomics · 2025Article
- Characterization of chemosensory genes in the subterranean pest Gryllotalpa Orientalis based on genome assembly and transcriptome comparison.BMC genomics · 2025Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Ionotropic receptors (IRs) are a highly divergent subfamily of ionotropic glutamate receptors (iGluR) and are conserved across Protostomia, a major branch of the animal kingdom that encompasses both Ecdysozoa and Lophothrochozoa. They are broadly expressed in peripheral sensory systems, concentrated in sensory dendrites, and function in chemosensation, thermosensation, and hygrosensation. As iGluRs, four IR subunits form a functional ion channel to detect environmental stimuli. Most IR receptors comprise individual stimulus-specific tuning receptors and one or two broadly expressed coreceptors. This review summarizes the discoveries of the structure of IR complexes and the expression and function of each IR, as well as discusses the future direction for IR studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.