Evidence map›Paper›PMID 33597826›Full record

ArticleTurkish journal of biology = Turk biyoloji dergisi2021

Current mutatome of SARS-CoV-2 in Turkey reveals mutations of interest.

Doğa Eskİer, Evren Akalp, Özlem Dalan, Gökhan KarakÜlah, Yavuz Oktay

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of biology = Turk biyoloji dergisi, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. COVID-19 modeling based on real geographic and population data.Turkish journal of medical sciences · 2023
    Article
  5. Article
  6. Article
  7. The effect of weekend curfews on epidemics: a Monte Carlo simulation.Turkish journal of biology = Turk biyoloji dergisi · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Doğa Eskİerİzmir Biomedicine and Genome Center (IBG), İzmir Turkey.ORCID https://orcid.org/0000-0003-0660-5791
Evren Akalpİzmir Biomedicine and Genome Center (IBG), İzmir Turkey.ORCID https://orcid.org/0000-0003-4725-7324
Özlem Dalanİzmir Biomedicine and Genome Center (IBG), İzmir Turkey.ORCID https://orcid.org/0000-0001-6581-5591
Gökhan KarakÜlahİzmir Biomedicine and Genome Center (IBG), İzmir Turkey.ORCID https://orcid.org/0000-0001-6706-1375
Yavuz Oktayİzmir Biomedicine and Genome Center (IBG), İzmir Turkey.ORCID https://orcid.org/0000-0002-0158-2693
Izmir Institute of Technology · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the underlying pathogen for the COVID-19 pandemic that has affected tens of millions of lives worldwide, SARS-CoV-2 and its mutations are among the most urgent research topics worldwide. Mutations in the virus genome can complicate attempts at accurate testing or developing a working treatment for the disease. Furthermore, because the virus uses its own proteins to replicate its genome, rather than host proteins, mutations in the replication proteins can have cascading effects on the mutation load of the virus genome. Due to the global, rapidly developing nature of the COVID-19 pandemic, local demographics of the virus can be difficult to accurately analyze and track, disproportionate to the importance of such information. Here, we analyzed available, high-quality genome data of SARS-CoV-2 isolates from Turkey and identified their mutations, in comparison to the reference genome, to understand how the local mutatome compares to the global genomes. Our results indicate that viral genomes in Turkey has one of the highest mutation loads and certain mutations are remarkably frequent compared to global genomes. We also made the data on Turkey isolates available on an online database to facilitate further research on SARS-CoV-2 mutations in Turkey.

Indexed as

coronavirusCOVID-19databasegenome analysismutation profilingSARS-CoV-2Turkey

Identifiers

PMID33597826
PMCPMC7877711
OpenAlexW3130240278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.