Evidence map›Paper›PMID 33597807›Full record

ArticleBreast cancer : basic and clinical research2020

Enhanced Recovery With Paravertebral and Transversus Abdominis Plane Blocks in Microvascular Breast Reconstruction.

Ryan Guffey, Grace Keane, Austin Y Ha, Rajiv Parikh, Elizabeth Odom, Li Zhang, Terence M Myckatyn

Open access · goldAbstract read
In one paragraph

Article in Breast cancer : basic and clinical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ryan GuffeyDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0001-8555-4122
Grace KeaneDivision of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Austin Y HaDivision of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0001-7113-1903
Rajiv ParikhDivision of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Elizabeth OdomDivision of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Li ZhangDepartment of Anesthesiology, Wuhan No. 1 Hospital, Wuhan, China.
Terence M MyckatynDivision of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Washington University in St. Louis · USWuhan No.1 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe have shown previously that a preoperative paravertebral nerve block is associated with improved postoperative recovery in microvascular breast reconstruction. The purpose of this study was to compare the outcomes of a complete enhanced recovery after surgery (ERAS) protocol with complete regional anesthesia coverage to our traditional care with paravertebral block. PATIENTS AND

methodsThis was a retrospective cohort study of 83 patients who underwent autologous breast reconstruction by T.M.M. between May 2014 and February 2018 at a tertiary academic center. Patients in the ERAS group were additionally administered acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), gabapentin, a transversus abdominis plane block (liposomal or plain bupivacaine), and primarily oral opioids postoperatively. The patients were mobilized earlier with more rapid diet progression. All patients received a preoperative paravertebral block.

resultsForty-four patients in the ERAS cohort were compared with 39 retrospective controls. The 2 groups were similar with respect to demographics and comorbidities. The ERAS cohort required significantly less opioids (291 vs 707 mg oral morphine equivalent,

conclusionsImplementation of a robust enhanced recovery protocol with complete regional anesthesia coverage was associated with significantly decreased opioid use despite unchanged pain scores, with improved markers of recovery including length of stay, time to oral only narcotics, and time to independent ambulation.

Indexed as

enhanced recoveryMicrovascular breast reconstructionmultimodal analgesia

Identifiers

PMID33597807
PMCPMC7863148
OpenAlexW3094045522

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.