Evidence map›Paper›PMID 33597801›Full record

ArticleSarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG2020

Sarcoidosis: a prospective observational cohort from Northern Alberta.

Dilini Vethanayagam, Jillian Peters, Emad Saad, Kimberley Mulchey, Ashley-Mae Gillson, Brian McNab, Maxine Farr-Jones, Tomasz Hruczkowski, Gregg Blevins, Richard Coulden and 2 more

Abstract read
In one paragraph

Article in Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dilini VethanayagamDivision of Pulmonary Medicine, University of Alberta.
Jillian PetersDivision of Pulmonary Medicine, University of Alberta.
Emad SaadDivision of Pulmonary Medicine, University of Alberta.
Kimberley MulcheyDivision of Pulmonary Medicine, University of Alberta.
Ashley-Mae GillsonDivision of Pulmonary Medicine, University of Alberta.
Brian McNabDivision of Pulmonary Medicine, University of Alberta.
Maxine Farr-JonesDivision of Pulmonary Medicine, University of Alberta.
Tomasz HruczkowskiDivision of Cardiology, University of Alberta.
Gregg BlevinsDivision of Neurology, University of Alberta.
Richard CouldenDepartment of Radiology and Diagnostic Imaging, University of Alberta.
Gavin OuditDivision of Cardiology, University of Alberta.
Jeremy BeachEmeritus, Division of Preventive Medicine, University of Alberta.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSarcoidosis is a multi-system disease reported to occur with a higher incidence in Alberta than many other health jurisdictions within and outside of Canada. The reasons for this higher incidence are currently not known. Exposure to beryllium can result in a clinically and radiologically identical disease to sarcoidosis. The purpose of our study was to identify patterns with potential occupational or environmental exposures to beryllium amongst individuals with sarcoidosis in Alberta through a tertiary referral center.

methodsA prospective observational study was carried out at the University of Alberta Hospital. Patients with confirmed sarcoidosis (stages 0-4) were recruited from subspecialty clinics (Respirology, Cardiology, Neurology and Occupational Health). A predetermined list of industries thought to involve potentially relevant exposures for the development of sarcoidosis was used to capture current and previous exposure history. Results were entered into a database and where possible verified by comparing with existing electronic medical records (including histories, physical examination, diagnostic imaging and physiology).

resultsA total of 45 patients were recruited, 25 men and 20 women. Of these, 84% of participants reported working in or being exposed to an industry/environment suspected of contributing to development of sarcoidosis over their lifetime. The most frequently reported exposures were within farming and agriculture (27%), oil and gas (20%), metalworking and handling animals (18%).

conclusionsAmongst this cohort, a high proportion reported working with a potentially relevant exposure. Individuals being assessed for sarcoidosis should have their most responsible physician elicit a detailed work and environmental history.

Indexed as

berylliumenvironmental exposureepidemiologyoccupational exposuresarcoidosis

Identifiers

PMID33597801
PMCPMC7883513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.