Evidence map›Paper›PMID 33597574›Full record

ArticleScientific reports2021

Endoscopic management versus radical nephroureterectomy for localized upper tract urothelial carcinoma in a high endemic region.

Yung-Tai Chen, Chih-Chin Yu, Hsin-Chih Yeh, Hsiang-Ying Lee, Yuan-Hong Jiang, Yu-Khun Lee, Chia-Hao Kuei, Chia-Chang Wu, Chao-Yuan Huang, Wei-Yu Lin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Yung-Tai ChenDepartment of Urology, Postal Hospital, Taipei, Taiwan.
Chih-Chin YuDivision of Urology, Department of Surgery, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Hsin-Chih YehDepartment of Urology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
Hsiang-Ying LeeDepartment of Urology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
Yuan-Hong JiangDepartment of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan.
Yu-Khun LeeDepartment of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan.
Chia-Hao KueiDivision of Urology, Department of Surgery, Cardinal Tien Hospital, New Taipei City, Taiwan.
Chia-Chang WuDepartment of Urology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Chao-Yuan HuangDepartment of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Wei-Yu LinDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital, Chia-Yi, Puzi City, Taiwan.
Cheng Kuang Yang *Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Yao Chou Tsai *Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. tsai1970523@yahoo.com.tw.
Taipei Medical University · TWTzu Chi University · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWChiayi Chang Gung Memorial Hospital · TWFu Jen Catholic University · TWNational Taiwan University Hospital · TWTaiwan Adventist Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim was to analyze the clinical and survival differences among patients who underwent the two main treatment modalities, endoscopic ablation and radical nephroureterectomy. This study examined all patients who had undergone endoscopic management and RNU between Jul. 1988 and Mar. 2019 from the Taiwan UTUC registry. The inclusion criteria were low stage UTUC in RNU and all cases in endoscopic managed UTUC with a curative intent. The demographic and clinical characteristics were included for analysis. In total, 84 cases in the endoscopic group and 272 cases in the RNU group were enrolled for final analysis. The median follow-up period were 33.5 and 42.0 months in endoscopic and RNU group, respectively (p = 0.082). Comparison of Kaplan-Meier estimated survival curves between groups, the endoscopic group was associated with similar overall survival (OS), cancer specific survival (CSS), and intravesical recurrence free survival (IVRS) but demonstrated inferior disease free survival (DFS) (p = 0.188 for OS, p = 0.493 for CSS and p < 0.001 for DFS). Endoscopic management of UTUC was as safe as RNU in UTUC endemic region.

Indexed as

AgedCarcinoma, Transitional CellEndoscopyFemaleHumansKaplan-Meier EstimateKidney NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalNephrectomyNephroureterectomyProgression-Free SurvivalRetrospective StudiesTaiwanTreatment Outcome

Identifiers

PMID33597574
PMCPMC7889610
OpenAlexW3133121677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.