Evidence map›Paper›PMID 33597315›Full record

ArticleAnatomy & cell biology2021

The amelioration of nicotine-induced reproductive impairment in male mouse by

Fahimeh Mohammadghasemi, Korosh Khanaki, Hamid Moravati, Masoumeh Faghani

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anatomy & cell biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Quercetin attenuates nicotine-induced ovarian and uterine dysfunction in rats.Clinical and experimental reproductive medicine · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fahimeh MohammadghasemiCellular & Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0002-7627-9787
Korosh KhanakiMedical Biotechnology Research Center, School of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0003-0733-6933
Hamid MoravatiAnimal Lab, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0002-3916-3611
Masoumeh FaghaniCellular & Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0001-6011-1958
Guilan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotine as a toxic agent in cigarette smoke impairs the reproductive system. Sambucus ebulus extract (SEE) is shown to have some beneficial effects such as antioxidant properties. The aim of this study was to evaluate the effects of SEE on the hormones of the pituitary-gonadal axis, lipid peroxidation index, antioxidant enzymes, spermatogenesis, and epididymal sperm parameters in male mice treated with nicotine. Adult male mice were divided into five groups; A: normal saline, B: 1 mg/kg nicotine, C: 1 mg/kg nicotine and 10 mg/kg SEE, D: 1 mg/kg nicotine and 50 mg/kg SEE, D: 1 mg/kg nicotine and 100 mg/kg SEE. Treatments lasted for 35 days. The spermicidal activity of SEE was tested

Indexed as

NicotineOxidative stressReproductionSambucus ebulusSpermatogenesis

Identifiers

PMID33597315
PMCPMC8225478
OpenAlexW3131147099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.