Evidence map›Paper›PMID 33597274›Full record

ArticleBMJ open quality2021

Bundle approach used to achieve zero central line-associated bloodstream infections in an adult coronary intensive care unit.

Poonam Gupta, Mincy Thomas, Ashfaq Patel, Reeba George, Leena Mathews, Seenu Alex, Siji John, Cherlyn Simbulan, Ma Leni Garcia, Sara Al-Balushi and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open quality, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 59 citations in OpenAlex.

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  5. Implementation of a care bundle improves PBC management.JHEP reports : innovation in hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Poonam GuptaQuality Improvement Department, Hamad Medical Corporation, Doha, Qatar PGupta1@hamad.qa.ORCID 0000-0002-9654-244X
Mincy ThomasNursing Department, Hamad Medical Corporation, Doha, Qatar.
Ashfaq PatelConsultant Cardiology, Hamad Medical Corporation, Doha, Qatar.
Reeba GeorgeNursing Department, Hamad Medical Corporation, Doha, Qatar.
Leena MathewsNursing Department, Hamad Medical Corporation, Doha, Qatar.
Seenu AlexNursing Department, Hamad Medical Corporation, Doha, Qatar.
Siji JohnNursing Department, Hamad Medical Corporation, Doha, Qatar.
Cherlyn SimbulanInfection Control Department, Hamad Medical Corporation, Doha, Qatar.
Ma Leni GarciaInfection Control Department, Hamad Medical Corporation, Doha, Qatar.
Sara Al-BalushiPharmacy Department, Hamad Medical Corporation, Doha, Qatar.
Mawahib El HassanConsultant Cardiology, Hamad Medical Corporation, Doha, Qatar.
Hamad Medical Corporation · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral venous catheterisation is commonly used in critical patients in intensive care units (ICU). It may cause complications and attribute to increase mortality and morbidity. At coronary ICU (CICU) of cardiac hospital, central line-associated bloodstream infection (CLABSI) rate was 2.82/1000 central line days in 2015 and 3.11/1000 central line days in 2016. Working in collaboration with Institute for Healthcare Improvement (IHI), we implemented evidence-based practices in the form of bundles in with the aim of eliminating CLABSI in CICU.

methodsIn collaboration with IHI, we worked on this initiative as multidisciplinary team and tested several changes. CLABSI prevention bundles were tested and implemented, single kit for line insertion, simulation-based training for line insertions, standardised and real-time bundle monitoring by direct observations are key interventions tested. We used model for improvement and changes were tested using small Plan-Do-Study-Act cycles. Surveillance methods and CLABSI definition used according to National Healthcare Safety Network.

resultsThe CLABSI rate per 1000 patient-days dropped from 3.1 per 1000 device-days to 0.4 per 1000 device-days. We achieved 757 days free of CLABSI in the unit till December 2018 when a single case happened. After that we achieved 602 free days till July 2020 and still counting.

conclusionsImplementation of evidence-based CLABSI prevention bundle and process monitoring by direct observation led to significant and subsequently sustained improvement in reducing CLABSI rate in adult CICU.

Indexed as

Catheterization, Central VenousCatheter-Related InfectionsSepsisAdultHumansInfection ControlIntensive Care Unitscompliancecontinuous quality improvementcritical careeducation

Identifiers

PMID33597274
PMCPMC7893645
OpenAlexW3130099168

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.