Evidence map›Paper›PMID 33597246›Full record

ArticleScience advances2021

The chromatin remodeler ISWI acts during

Naihua N Gong, Leela Chakravarti Dilley, Charlette E Williams, Emilia H Moscato, Milan Szuperak, Qin Wang, Matthew Jensen, Santhosh Girirajan, Tiong Yang Tan, Matthew A Deardorff and 3 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Sleep regulation inFrontiers in neuroscience · 2026
    Review
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  6. Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Neurobiology of sleep and circadian rhythms · 2023
    Article
  13. Pleiotropic effects of a high confidence Autism Spectrum Disorder gene,Neurobiology of sleep and circadian rhythms · 2023
    Article
  14. Article
  15. Review
  16. eLife · 2021
    Article
  17. Pathogenic variants inScience advances · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Naihua N GongDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-2107-0166
Leela Chakravarti DilleyDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-8115-6821
Charlette E WilliamsDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-8055-1210
Emilia H MoscatoDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Milan SzuperakDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-7910-2533
Qin WangRaymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Matthew JensenDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-5153-8543
Santhosh GirirajanDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
Tiong Yang TanVictorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Australia.
Matthew A DeardorffDivision of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0002-1542-1305
Dong LiCenter for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0002-2265-6727
Yuanquan SongRaymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0001-7699-2059
Matthew S KayserDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. kayser@pennmedicine.upenn.edu.ORCID 0000-0003-2359-4967
University of Pennsylvania · USChildren's Hospital of Philadelphia · USPennsylvania State University · USThe University of Melbourne · AU

Funding

Training in Sleep & Sleep DisordersT32HL007953 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI David Menassah Raizen, AMY M SAWYER · 2000 to 2026
$10.6M
Genomic basis of phenotypic variability of genomic disordersR01GM121907 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI GIRIRAJAN, SANTHOSH · 2017 to 2025
$5.2M
Building brains in our sleep: A Drosophila larval platform for examining sleep and neurogenesisDP2NS111996 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI KAYSER, MATTHEW S · 2018 to 2018
$2.4M
A critical period of sleep required for normal brain developmentK08NS090461 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI KAYSER, MATTHEW S · 2014 to 2018
$952k
NHLBI NIH HHS T32 HL007953NIGMS NIH HHS R01 GM121907NINDS NIH HHS DP2 NS111996NINDS NIH HHS K08 NS090461
6 · The paper itself

Abstract

Sleep disruptions are among the most commonly reported symptoms across neurodevelopmental disorders (NDDs), but mechanisms linking brain development to normal sleep are largely unknown. From a

Indexed as

ChromatinDrosophilaAnimalsChromatin Assembly and DisassemblyChromosomesHumansSleepChromatin

Identifiers

PMID33597246
PMCPMC7888929
OpenAlexW3131168421

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.