Evidence map›Paper›PMID 33597229›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2021

Prematurity and postnatal alterations in intermittent hypoxaemia.

Juliann M Di Fiore, Vidhi Shah, Abhijit Patwardhan, Abdus Sattar, Shengxuan Wang, Thomas Raffay, Richard J Martin, Elie G Abu Jawdeh

Abstract readMulticenter Study
In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Intermittent Hypoxemia and Brain Injury Biomarker S100B in Preterm Infants.medRxiv : the preprint server for health sciences · 2025
    Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juliann M Di FioreDepartment of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA.
Vidhi ShahDivision of Neonatology, Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA.
Abhijit PatwardhanDepartment of Biomedical Engineering, University of Kentucky, Lexington, Kentucky, USA.
Abdus SattarDepartment of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA.
Shengxuan WangDepartment of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA.
Thomas RaffayDepartment of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA.
Richard J MartinDepartment of Pediatrics, Rainbow Babies Childrens Hospital, Cleveland, Ohio, USA.
Elie G Abu JawdehDepartment of Pediatrics, University of Kentucky, Lexington, Kentucky, USA elieabujawdeh@gmail.com.ORCID http://orcid.org/0000-0003-4414-7007

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
KENTUCKY CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCEUL1RR033173 · NCRR · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2011 to 2011
$3.5M
S-nitrosoglutathione reductase and airways hyperreactivity in murine bronchopulmonary dysplasiaK08HL133459 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI RAFFAY, THOMAS MICHAEL · 2017 to 2021
$821k
NCATS NIH HHS UL1 TR001998NCRR NIH HHS UL1 RR033173NHLBI NIH HHS K08 HL133459
6 · The paper itself

Abstract

Intermittent hypoxaemia (IH) events are well described in extremely preterm infants, but the occurrence of IH patterns in more mature preterm infants remains unclear. The objective of this study was to characterise the effect of gestational age on early postnatal patterns of IH in extremely (<28 weeks), very (28-<32 weeks) and moderately (32-<34 weeks) preterm infants. As expected, extremely preterm infants had a significantly higher frequency of IH events of longer durations and greater time with hypoxaemia versus very and moderately preterm infants. In addition, the postnatal decrease in IH duration was comparable in the very and moderately preterm infants. This progression of IH events should assist clinicians and families in managing expectations for resolution of IH events during early postnatal life.

Indexed as

Gestational AgeHumansHypoxiaInfant, Extremely PrematureInfant, NewbornInfant, PrematureInfant, Premature, DiseasesRetrospective StudiesTime Factorshealth services researchneonatology

Identifiers

PMID33597229
PMCPMC8462666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.