Evidence map›Paper›PMID 33597114›Full record

ArticleVaccine2021

Influenza vaccination coverage among persons seeking outpatient medical care for acute respiratory illness in five states in the United States, 2011-2012 through 2018-2019.

Michael J Wu, Jessie R Chung, Sara S Kim, Michael L Jackson, Lisa A Jackson, Edward A Belongia, Huong Q McLean, Manjusha Gaglani, Michael Reis, Madhava Beeram and 8 more

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Estimating county-level flu vaccination in the United States.medRxiv : the preprint server for health sciences · 2023
    Article
  3. Influenza Vaccine Effectiveness Against Influenza A(H3N2)-Related Illness in the United States During the 2021-2022 Influenza Season.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Michael J WuInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Jessie R ChungInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Sara S KimInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Michael L JacksonKaiser Permanente Washington Health Research Institute, Seattle, WA, United States.
Lisa A JacksonKaiser Permanente Washington Health Research Institute, Seattle, WA, United States.
Edward A BelongiaMarshfield Clinic Research Institute, Marshfield, WI, United States.
Huong Q McLeanMarshfield Clinic Research Institute, Marshfield, WI, United States.
Manjusha GaglaniBaylor Scott and White Health, Texas A&M University College of Medicine, Temple, TX, United States.
Michael ReisBaylor Scott and White Health, Texas A&M University College of Medicine, Temple, TX, United States.
Madhava BeeramBaylor Scott and White Health, Texas A&M University College of Medicine, Temple, TX, United States.
Emily T MartinUniversity of Michigan and Henry Ford Health System, Ann Arbor, MI, United States.
Arnold S MontoUniversity of Michigan and Henry Ford Health System, Ann Arbor, MI, United States.
Mary Patricia NowalkUniversity of Pittsburgh Schools of the Health Sciences and UPMC, Pittsburgh, PA, United States.
Richard ZimmermanUniversity of Pittsburgh Schools of the Health Sciences and UPMC, Pittsburgh, PA, United States.
Tammy A SantibanezImmunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
James A SingletonImmunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Manish PatelInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: aul3@cdc.gov.
Brendan FlanneryInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Centers for Disease Control and Prevention · USBaylor Scott & White Health · USHenry Ford Health System · USKaiser Permanente Washington Health Research Institute · USMarshfield Clinic · USUniversity of Pittsburgh · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
US Influenza Vaccine Effectiveness NetworkU01IP001034 · IP · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MONTO, ARNOLD S · 2016 to 2020
$10.0M
Annual Estimates of Influenza Vaccine Effectiveness and Evaluation of Immune Response in a Wisconsin PopulationU01IP001038 · IP · MARSHFIELD CLINIC RESEARCH FOUNDATION · PI BELONGIA, EDWARD · 2016 to 2020
$8.0M
Outpatient VE for seasonal flu, pandemic flu and RSV in a large, diverse networkU01IP001035 · IP · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZIMMERMAN, RICHARD K · 2016 to 2020
$7.8M
Mandatory_Estimates of Vaccine Effectiveness Against Medically-Attended, PCR-Confirmed Influenza in West South Central U.S.U01IP001039 · IP · SCOTT AND WHITE MEMORIAL HOSPITAL · PI GAGLANI, MANJUSHA · 2016 to 2020
$6.5M
Core_RT-PCR based Case-Control: Apt Measure of Influenza Vaccine EffectivenessU01IP000473 · IP · SCOTT AND WHITE MEMORIAL HOSPITAL · PI GAGLANI, MANJUSHA · 2011 to 2015
$4.0M
ACL HHS U01IP001039Intramural CDC HHS CC999999NCATS NIH HHS UL1 TR001857NCIRD CDC HHS U01 IP000473NCIRD CDC HHS U01 IP001034NCIRD CDC HHS U01 IP001035NCIRD CDC HHS U01 IP001038NCIRD CDC HHS U01 IP001039
6 · The paper itself

Abstract

backgroundIn the United States (U.S.), annual influenza vaccination has been recommended for all persons aged ≥6 months with the Healthy People 2020 coverage target of 70%. However, vaccination coverage has remained around 42-49% during the past eight influenza seasons. We sought to quantify influenza vaccination coverage and factors associated with vaccination in persons seeking outpatient medical care for an acute respiratory illness (ARI).

methodsWe enrolled outpatients aged ≥6 months with ARI from >50 U.S. clinics from 2011 to 2012 through 2018-2019 influenza seasons and tested for influenza with molecular assays. Vaccination status was based on documented receipt of the current season's influenza vaccine. We estimated vaccination coverage among influenza-negative study participants by study site, age, and season, and compared to state-level influenza coverage estimates in the general population based on annual immunization surveys. We used multivariable logistic regression to examine factors independently associated with receipt of influenza vaccines.

resultsWe enrolled 45,424 study participants with ARI who tested negative for influenza during the study period. Annual vaccination coverage among influenza-negative ARI patients and the general population in the participating states averaged 55% (range: 47-62%), and 52% (range: 46-54%), respectively. Among enrollees, coverage was highest among adults aged ≥65 years (82%; range, 80-85%) and lowest among adolescents aged 13-17 years (38%; range, 35-41%). Factors significantly associated with non-vaccination included non-White race, no college degree, exposure to cigarette smoke, absence of high-risk conditions, and not receiving prior season influenza vaccine.

conclusionsInfluenza vaccination coverage over eight seasons among outpatients with non-influenza respiratory illness was slightly higher than coverage in the general population but 15% lower than national targets. Increased efforts to promote vaccination especially in groups with lower coverage are warranted to attain optimal health benefits of influenza vaccine.

Indexed as

Influenza, HumanInfluenza VaccinesAdolescentAdultAged, 80 and overHumansInfantOutpatientsPopulation SurveillanceSeasonsUnited StatesVaccinationVaccination CoverageInfluenza VaccinesAdultChildCoverageInfluenzaRisk factorsVaccination

Identifiers

PMID33597114
PMCPMC8573763
OpenAlexW3132264576

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.