SynthesisBMC pediatrics2021
Oral feeding for infants and children receiving nasal continuous positive airway pressure and high flow nasal cannula: a systematic review.
Synthesis in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Breastfeeding infants with CHD: an evidence summary and recommendations from the Cardiac Newborn Neuroprotective Network, a special interest group of the Cardiac Neurodevelopmental Outcome Collaborative.Cardiology in the young · 2025Guideline
- A clinical consensus guideline for nutrition in infants with congenital diaphragmatic hernia from birth through discharge.Journal of perinatology : official journal of the California Perinatal Association · 2024Guideline
- OcclusiveEuropean respiratory review : an official journal of the European Respiratory Society · 2026Review
- Reach, implementation fidelity, and safety of bubble continuous positive airway pressure (bCPAP) therapy in children with severe pneumonia in Pakistan.PLOS global public health · 2026Article
- Article
- Enteral feeding in pediatric patients with bronchiolitis requiring non-invasive support via nasal interface.Pediatric research · 2025Article
- Oral Feeding of NICU Infants: A Global Survey of Current Practices and the Potential of Cold Milk Feeding Intervention.Nutrients · 2025Article
- Perceptions of hospital feeding practices among mothers of infants with severe pneumonia in Malawi: a qualitative descriptive study.BMJ open · 2025Observational
- Feeding Infants on Noninvasive Respiratory Support: Practice at One Academic Medical Center.American journal of speech-language pathology · 2025Article
- Speech-language therapists' views of oral feeding of infants on high-flow oxygen.Health SA = SA Gesondheid · 2025Article
- Oral feeding practices in medically complex infants receiving prolonged high-flow nasal cannula support: A retrospective cohort study.Journal of paediatrics and child health · 2024Article
- Introduction of oral feeding in premature infants on high flow nasal cannula in a level IV neonatal intensive care unit: a quality improvement initiative.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Oral Nutrition During Continuous Albuterol for Pediatric Critical Asthma: A Matched Cohort Study.Pediatric gastroenterology, hepatology & nutrition · 2024Article
- Swallowing and feeding of young children on high-flow oxygen therapy.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2024Article
- Neonatal Birthweight Spectrum: Maternal Risk Factors and Pregnancy Outcomes in Saudi Arabia.Medicina (Kaunas, Lithuania) · 2024Article
- Developmental care pathway for hospitalised infants with CHD: on behalf of the Cardiac Newborn Neuroprotective Network, a Special Interest Group of the Cardiac Neurodevelopmental Outcome Collaborative.Cardiology in the young · 2023Article
- A Survey of Feeding Practices During High-Flow Nasal Cannula Oxygen Therapy.Respiratory care · 2023Article
- Noninvasive Respiratory Support Effects on Sighs in Preterm Infants by Electrical Impedance Tomography.Indian journal of pediatrics · 2023Article
- Oral stimulation for promoting oral feeding in preterm infants.The Cochrane database of systematic reviews · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this systematic review was to determine whether introduction of oral feeding for infants and children receiving nasal continuous positive airway pressure (nCPAP) or high flow nasal cannula (HFNC) respiratory support facilitates achievement of full oral feeding without adverse effects, compared to no oral feeding (NPO; nil per oral) on CPAP or HFNC.
methodsA protocol was lodged with the PROSPERO International Prospective Register of Systematic Reviews. We searched Medline, Embase, CINAHL, CENTRAL and AustHealth from database inception to 10th June 2020. Study population included children (preterm to < 18 years) on nCPAP or HFNC who were orally feeding. Primary outcomes included full or partial oral feeding and oropharyngeal aspiration. Secondary outcomes examined adverse events including clinical signs of aspiration, aspiration pneumonia and deterioration in respiratory status.
resultsThe search retrieved 1684 studies following duplicate removal. Title and abstract screening identified 70 studies for full text screening and of these, 16 were included in the review for data extraction. Methods of non-invasive ventilation (NIV) included nCPAP (n = 6), nCPAP and HFNC (n = 5) and HFNC (n = 5). A metanalysis was not possible as respiratory modes and cohorts were not comparable. Eleven studies reported on adverse events. Oral feeding safety was predominantly based on retrospective data from chart entries and clinical signs, with only one study using an instrumental swallow evaluation (VFSS) to determine aspiration status.
conclusionsFindings are insufficient to conclude whether commencing oral feeding whilst on nCPAP or HFNC facilitates transition to full oral feeding without adverse effects, including oropharyngeal aspiration. Further research is required to determine the safety and efficacy of oral feeding on CPAP and HFNC for infants and children.
trial registrationPROSPERO registration number: CRD42016039325 .
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.