ArticleBMC plant biology2021
Integrated metabolic profiling and transcriptome analysis of pigment accumulation in Lonicera japonica flower petals during colour-transition.
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 72 citations in OpenAlex.
- Mechanisms underlying green flower formation.Horticulture research · 2026Article
- Integrated Omics Analysis Revealed the Differential Metabolism of Pigments in Three Varieties ofInternational journal of molecular sciences · 2025Article
- Integrative Analyses of Metabolome and Transcriptome Reveals Apocarotenoid and Flavonoid Biosynthesis During Saffron (Food science & nutrition · 2025Article
- Carotenoid metabolomic and transcriptomic analyses provide insights into the flower color transition in Lonicera macranthoides.BMC biotechnology · 2025Article
- Article
- Transcriptome analysis reveals the expression of genes involved in the formation of petal variegation in Impatiens morsei.Scientific reports · 2025Article
- Building beauty: Understanding how hormone signaling regulates petal patterning and morphogenesis.The Plant journal : for cell and molecular biology · 2025Review
- Integrated Genetic Diversity and Multi-Omics Analysis of Colour Formation in Safflower.International journal of molecular sciences · 2025Article
- Transcriptomic and metabolomic analyses of threeFrontiers in plant science · 2025Article
- Integrated metabolome and transcriptome analysis provides clues to fruit color formation of yellow, orange, and red bell pepper.Scientific reports · 2024Article
- Transcriptomics and metabolomics revealed the molecular basis of the color formation in the roots ofHeliyon · 2024Article
- Transcriptomic and metabolomic profiling reveals molecular regulatory network involved in flower development and phenotypic changes in two3 Biotech · 2024Article
- Integrative metabolome and transcriptome analyses reveal the coloration mechanism in Camellia oleifera petals with different color.BMC plant biology · 2024Article
- Application of metabolomics in quality control of traditional Chinese medicines: a review.Frontiers in plant science · 2024Review
- Integrated transcriptome and metabolome analysis unveils the mechanism of color-transition in Edgeworthia chrysantha tepals.BMC plant biology · 2023Article
- Analyzing Morphology, Metabolomics, and Transcriptomics Offers Invaluable Insights into the Mechanisms of Pigment Accumulation in the Diverse-Colored Labellum Tissues ofPlants (Basel, Switzerland) · 2023Article
- A Comprehensive Quality Analysis of Different Colors of Medicinal and Edible Honeysuckle.Foods (Basel, Switzerland) · 2023Article
- Characterization Variation of the Differential Coloring Substances in Rapeseed Petals with Different Colors Using UPLC-HESI-MS/MS.Molecules (Basel, Switzerland) · 2023Article
- Transcriptomic Analysis Reveals the Regulatory Mechanism of Color Diversity inPlants (Basel, Switzerland) · 2023Article
- Integrated metabolome and transcriptome analysis unveils novel pathway involved in the fruit coloration of Nitraria tangutorum Bobr.BMC plant biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPlants have remarkable diversity in petal colour through the biosynthesis and accumulation of various pigments. To better understand the mechanisms regulating petal pigmentation in Lonicera japonica, we used multiple approaches to investigate the changes in carotenoids, anthocyanins, endogenous hormones and gene expression dynamics during petal colour transitions, i.e., green bud petals (GB_Pe), white flower petals (WF_Pe) and yellow flower petals (YF_Pe).
resultsMetabolome analysis showed that YF_Pe contained a much higher content of carotenoids than GB_Pe and WF_Pe, with α-carotene, zeaxanthin, violaxanthin and γ-carotene identified as the major carotenoid compounds in YF_Pe. Comparative transcriptome analysis revealed that the key differentially expressed genes (DEGs) involved in carotenoid biosynthesis, such as phytoene synthase, phytoene desaturase and ζ-carotene desaturase, were significantly upregulated in YF_Pe. The results indicated that upregulated carotenoid concentrations and carotenoid biosynthesis-related genes predominantly promote colour transition. Meanwhile, two anthocyanins (pelargonidin and cyanidin) were significantly increased in YF_Pe, and the expression level of an anthocyanidin synthase gene was significantly upregulated, suggesting that anthocyanins may contribute to vivid yellow colour in YF_Pe. Furthermore, analyses of changes in indoleacetic acid, zeatin riboside, gibberellic acid, brassinosteroid (BR), methyl jasmonate and abscisic acid (ABA) levels indicated that colour transitions are regulated by endogenous hormones. The DEGs involved in the auxin, cytokinin, gibberellin, BR, jasmonic acid and ABA signalling pathways were enriched and associated with petal colour transitions.
conclusionOur results provide global insight into the pigment accumulation and the regulatory mechanisms underlying petal colour transitions during the flower development process in L. japonica.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.