Evidence map›Paper›PMID 33596665›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Ceramide Scores Predict Cardiovascular Risk in the Community.

Vlad C Vasile, Jeffrey W Meeusen, Jose R Medina Inojosa, Leslie J Donato, Christopher G Scott, Meredith S Hyun, Manlio Vinciguerra, Richard R Rodeheffer, Francisco Lopez-Jimenez, Allan S Jaffe

Open access · bronzeAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Sphingolipids and Atherosclerosis.Current atherosclerosis reports · 2026
    Review
  8. Ceramides versus standard methods in prediction of subclinical atherosclerosis.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2026
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. The Role of Ceramides in Metabolic and Cardiovascular Diseases.Journal of cardiovascular development and disease · 2026
    Review
  15. Article
  16. Ceramides and Oxidized Lipids: Convergent Mediators of Cardiometabolic Pathogenesis.Cardiovascular & hematological agents in medicinal chemistry · 2026
    Article
  17. Review
  18. Article
  19. Ceramide as a Biomarker for HFpEF in Women: Menopause, Aging, and Pregnancy.International journal of molecular sciences · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Vlad C VasileDepartment of Laboratory Medicine and Pathology (V.C.V., J.W.M., L.J.D., A.S.J.), Mayo Clinic College of Medicine, Rochester, MN.
Jeffrey W MeeusenDepartment of Laboratory Medicine and Pathology (V.C.V., J.W.M., L.J.D., A.S.J.), Mayo Clinic College of Medicine, Rochester, MN.
Jose R Medina InojosaDepartment of Cardiovascular Diseases (V.C.V., J.R.M.J., R.R.R., F.L.-J., A.S.J.), Mayo Clinic College of Medicine, Rochester, MN.
Leslie J DonatoDepartment of Laboratory Medicine and Pathology (V.C.V., J.W.M., L.J.D., A.S.J.), Mayo Clinic College of Medicine, Rochester, MN.
Christopher G ScottDepartment of Biomedical Statistics and Informatics (C.G.S., M.S.H.), Mayo Clinic College of Medicine, Rochester, MN.
Meredith S HyunDepartment of Biomedical Statistics and Informatics (C.G.S., M.S.H.), Mayo Clinic College of Medicine, Rochester, MN.
Manlio VinciguerraInternational Clinical Research Center (ICRC [Human Bridge for Strengthening Integration of ICRC into European Research Area]), St. Anne's University Hospital, Brno, Czech Republic (M.V.).
Richard R RodehefferDepartment of Cardiovascular Diseases (V.C.V., J.R.M.J., R.R.R., F.L.-J., A.S.J.), Mayo Clinic College of Medicine, Rochester, MN.
Francisco Lopez-JimenezDepartment of Cardiovascular Diseases (V.C.V., J.R.M.J., R.R.R., F.L.-J., A.S.J.), Mayo Clinic College of Medicine, Rochester, MN.
Allan S JaffeDepartment of Laboratory Medicine and Pathology (V.C.V., J.W.M., L.J.D., A.S.J.), Mayo Clinic College of Medicine, Rochester, MN.
Mayo Clinic · USInternational Clinical Research Center, St. Anne's University Hospital Brno · CZMayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

PREVALENCE OF ASYMPTOMATIC VENTRICULAR DYSFUNCTIONR01HL055502 · NHLBI · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI RODEHEFFER, RICHARD J. · 1997 to 2004
$2.7M
NHLBI NIH HHS R01 HL055502
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AgedBiomarkersCeramidesCoronary Artery DiseaseDisease ProgressionFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedMinnesotaMyocardial InfarctionPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentBiomarkersCeramidesatherosclerosiscardiovascular diseaseceramidecoronary artery diseaserisk factors

Identifiers

PMID33596665
PMCPMC8939859
OpenAlexW3130193990

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.