Evidence map›Paper›PMID 33596644›Full record

ArticleHaematologica2021

The TRPV2 channel mediates Ca2+ influx and the Δ9-THC-dependent decrease in osmotic fragility in red blood cells.

Anouar Belkacemi, Claudia Fecher Trost, René Tinschert, Daniel Flormann, Mahsa Malihpour, Christian Wagner, Markus R Meyer, Andreas Beck, Veit Flockerzi

Abstract readLetter
In one paragraph

Article in Haematologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Role of channels in the ObioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Lysis of human erythrocytes due to Piezo1-dependent cytosolic calcium overload as a mechanism of circulatory removal.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. The Putative Role of the Transient Receptor Potential Ion Channel of Vanilloid Type 2 in Red Blood Cell Storage Lesions.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2024
    Article
  8. Article
  9. Current pharmaceutical design · 2024
    Article
  10. Article
  11. Article
  12. Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.bioRxiv : the preprint server for biology · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Altered CaCells · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anouar BelkacemiExperimentelle und Klinische Pharmakologie und Toxikologie und Präklinisches Zentrum für Molekulare Signalverarbeitung (PZMS), Universität des Saarlandes, 66421 Homburg.
Claudia Fecher TrostExperimentelle und Klinische Pharmakologie und Toxikologie und Präklinisches Zentrum für Molekulare Signalverarbeitung (PZMS), Universität des Saarlandes, 66421 Homburg.
René TinschertExperimentelle und Klinische Pharmakologie und Toxikologie und Präklinisches Zentrum für Molekulare Signalverarbeitung (PZMS), Universität des Saarlandes, 66421 Homburg.
Daniel FlormannExperimentalphysik, Universität des Saarlandes, 66123 Saarbrücken.
Mahsa MalihpourExperimentelle und Klinische Pharmakologie und Toxikologie und Präklinisches Zentrum für Molekulare Signalverarbeitung (PZMS), Universität des Saarlandes, 66421 Homburg.
Christian WagnerExperimentalphysik, Universität des Saarlandes, 66123 Saarbrücken, Deutschland; University of Luxembourg, Physics and Materials Science Research Unit, L-1511, Luxembourg.
Markus R MeyerExperimentelle und Klinische Pharmakologie und Toxikologie und Präklinisches Zentrum für Molekulare Signalverarbeitung (PZMS), Universität des Saarlandes, Homburg.
Andreas BeckExperimentelle und Klinische Pharmakologie und Toxikologie und Präklinisches Zentrum für Molekulare Signalverarbeitung (PZMS), Universität des Saarlandes, 66421 Homburg.
Veit FlockerziExperimentelle und Klinische Pharmakologie und Toxikologie und Präklinisches Zentrum für Molekulare Signalverarbeitung (PZMS), Universität des Saarlandes, 66421 Homburg. Veit.Flockerzi@uks.eu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CalciumErythrocytesOsmotic FragilityCalcium

Identifiers

PMID33596644
PMCPMC8327723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.