Evidence map›Paper›PMID 33596623›Full record

Trial reportKorean journal of ophthalmology : KJO2021

Transepithelial Laser versus Alcohol Assisted Photorefractive Keratectomy Safety and Efficacy: 1-Year Follow-up of a Contralateral Eye Study.

Hesham Mohamed Gharieb, Mo'mena Ahmad A Awad-Allah, Anas Adel Ahmed, Ihab Saad Othman

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Korean journal of ophthalmology : KJO, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Corneal clarity and biomechanical stability after mitomycin C-assisted photorefractive keratectomy in low, moderate, and high myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Article
  3. One-Year Visual and Refractive Outcomes of SmartPulseJournal of clinical medicine · 2024
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hesham Mohamed GhariebDepartment of Ophthalmology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Mo'mena Ahmad A Awad-AllahDepartment of Ophthalmology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Anas Adel AhmedEye World Hospital, Dokki, Giza, Egypt.
Ihab Saad OthmanEye World Hospital, Dokki, Giza, Egypt.
Ain Shams University · EGCairo University · EGHelwan University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare single-step transepithelial photorefractive keratectomy (TPRK) to conventional alcohol assisted epithelial removal then photorefractive keratectomy (AAPRK) regarding pain, epithelial healing, visual acuity, corneal haze measured subjectively and objectively, higher order aberrations changes, contrast sensitivity and vector analysis of astigmatic correction with one year follow-up.

methodsA prospective double-blind randomized study of 29 subjects (58 eyes) who underwent myopic aberration-free laser correction by smart pulse technology using Schwind Amaris 1050 Hz with 1-year follow-up. Right eye was randomly treated by AAPRK or TPRK. Postoperative assessment was performed on day 1 and 3, at 1st week, and 1st, 3rd, 6th, and 12th months. Patients were assessed for pain, epithelial healing, visual acuity, corneal haze, astigmatic correction, higher order aberrations and contrast sensitivity.

resultsEpithelial healing was complete by the 3rd day in 62.1% of AAPRK eyes and in 89.7% of TPRK eyes. First day postoperative pain was higher in TPRK group (p = 0.0134). The decimal uncorrected visual acuity at 12 months was 1.47 ± 0.39 and 1.57 ± 0.38 in the AAPRK and TPRK groups respectively (p = 0.3719). Post-photorefractive keratectomy haze reached a final level of 0.04 ± 0.14 and 0.02 ± 0.1 in AAPRK and TPRK groups respectively (p = 0.5607). Contrast sensitivity was comparable in low and high frequency cycles per degree. Vector analysis of astigmatic correction showed correction index at one year of 0.99 and 1.05 for AAPRK and TPRK groups respectively.

conclusionsAlcohol assisted and transepithelial photorefractive keratectomy have comparable results regarding safety and efficacy.

Indexed as

Epithelium, CornealPhotorefractive KeratectomyDouble-Blind MethodFollow-Up StudiesHumansLasers, ExcimerProspective StudiesRefraction, OcularTreatment OutcomeAlcohol assisted photorefractive keratectomyContrast sensitivitySmart pulse technologyTransepithelial photorefractive keratectomyVector analysis

Identifiers

PMID33596623
PMCPMC8046614
OpenAlexW3130056044

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.