ArticleCell reports2021
Examining the role of olfaction in dietary choice.
Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of the biological mediators of fat taste and smell.Physiological reviews · 2023Pooled it
- Olfactory dysfunction in obesity and type 2 diabetes: mechanistic insights from preclinical models.Diabetologia · 2026Review
- Effect of theFoods (Basel, Switzerland) · 2026Article
- A midbrain-to-ventral-striatum dopaminergic pathway orchestrates odor-guided insect predation in mice.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Prolonged exposure to food odors suppresses feeding via an olfactory bulb-to-hypothalamus circuit.Nature communications · 2025Article
- Olfactory function in diabetes mellitus.Journal of clinical & translational endocrinology · 2024Review
- An anatomically distinct subpopulation of orexin neurons project from the lateral hypothalamus to the olfactory bulb.The Journal of comparative neurology · 2023Article
- Food odor perception promotes systemic lipid utilization.Nature metabolism · 2022Article
- Progress in the Development of Detection Strategies Based on Olfactory and Gustatory Biomimetic Biosensors.Biosensors · 2022Review
- Acute Fasting Modulates Food-Seeking Behavior and Neural Signaling in the Piriform Cortex.Nutrients · 2022Article
- Post-oral sensing of fat increases food intake and attenuates body weight defense.Cell reports · 2021Article
- The Orexigenic Force of Olfactory Palatable Food Cues in Rats.Nutrients · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Obesity is frequently caused by calorie-rich dietary choices across the animal kingdom. As prandial preference toward a high-fat diet develops in mice, an anti-preference or devaluation of a nutritionally balanced but less palatable standard chow diet occurs concomitantly. Although mechanistic insights underlying devaluation have been observed physiologically in the brain, it is unclear how peripheral sensory processing affects food choice. Because olfactory cues and odor perception help coordinate food preference and intake, we determine the role of smell in the targeted consumption of a high-fat diet and simultaneous devaluation of a standard chow diet. Using inaccessible food and loss-of-function manipulations, we find that olfactory information is neither sufficient nor necessary for both the acute and chronic selection of high-fat diet and coincident diminished value of standard diet. This work suggests alternative means are behind the immediate and sustained consumption of high-fat diet and concurrent standard diet devaluation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.