ArticleJournal of applied clinical medical physics2021
The surface area effect: How the intermediate dose spill depends on the PTV surface area in SRS.
Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Target-volume-based prescription selection for specified adverse-effect levels in automated stereotactic radiosurgery.Physics and imaging in radiation oncology · 2026Article
- HyperArc Automated Stereotactic Radiosurgery Planning Enables Accurate a Priori Fractionation Scheme Selection via Adherence to HyTEC Toxicity Thresholds.Advances in radiation oncology · 2025Article
- Exploring feasibility criteria for stereotactic radiosurgical treatment of multiple brain metastases using five linac machines.Journal of applied clinical medical physics · 2024Article
- How to estimate R50% for cranial SRS/SRT cases with overlapping 50% isodose volumes: A proposed system.Journal of applied clinical medical physics · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStereotactic radiosurgery (SRS) is rapidly becoming the standard of care for many intracranial targets. The characteristics of the planning target volume (PTV) can affect the intermediate dose spill and thus normal brain volume dose which is correlated with brain toxicity. R50% (volume receiving 50% of prescription dose divided by PTV volume) is a useful metric to quantify the intermediate dose spill. We propose a novel understanding of how the PTV surface area (SA
methodsUsing a phantom model provided by a computed tomography (CT) of the IROC Head Phantom® and Eclipse® Treatment Planning System, we investigate the relationship of R50% and SA
resultsThe SRS phantom study indicates good correlation between the plan R50% and SA
conclusionsWe demonstrate dependence of the intermediate dose spill measured by R50% on the SA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.