Evidence map›Paper›PMID 33595899›Full record

ArticleMaternal & child nutrition2021

Prenatal dietary diversity may influence underweight in infants in a Ugandan birth-cohort.

Isabel Madzorera, Shibani Ghosh, Molin Wang, Wafaie Fawzi, Sheila Isanaka, Ellen Hertzmark, Grace Namirembe, Bernard Bashaasha, Edgar Agaba, Florence Turyashemererwa and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Maternal & child nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04233944 (Effectiveness of Integrated Livelihood and Nutrition Interventions to Improve Maternal and Child Nutrition and Health in Rural Uganda), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04233944 terminatednot on this map

Effectiveness of Integrated Livelihood and Nutrition Interventions to Improve Maternal and Child Nutrition and Health in Rural Uganda: A Birth Cohort Study

TypeobservationalSponsorTufts UniversityRan2014 to 2016Enrolled5,044ConditionsBirth Outcomes, Stunting, Wasting, Anemia
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Maternal Aflatoxin Exposure, Birth Outcomes, and Infant Growth in Uganda.The American journal of tropical medicine and hygiene · 2026
    Article
  6. Article
  7. Review
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  9. Maternal Dietary Diversity and Birth Weight in Offspring: Evidence from a Chinese Population-Based Study.International journal of environmental research and public health · 2023
    Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Isabel MadzoreraDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0001-7226-5997
Shibani GhoshGerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
Molin WangDepartments of Epidemiology and Biostatistics, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Wafaie FawziDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
Sheila IsanakaDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
Ellen HertzmarkDepartment of Global Health and Population, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
Grace NamirembeGerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
Bernard BashaashaDepartment of Agribusiness and Natural Resource Economics, College of Agricultural and Environmental Sciences, Makerere University, Kampala, Uganda.
Edgar AgabaUSAID Feed the Future Innovation Lab for Nutrition, Tufts University, Boston, Massachusetts, USA.
Florence TuryashemererwaDepartment of Agribusiness and Natural Resource Economics, College of Agricultural and Environmental Sciences, Makerere University, Kampala, Uganda.
Patrick WebbGerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
Christopher DugganDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
Tufts University · USHarvard University · USMakerere University · UGBoston Children's Hospital · USBrigham and Women's Hospital · USHarvard Global Health Institute · US

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Patient-oriented Research in Pediatric Diarrheal DiseasesK24DK104676 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI DUGGAN, CHRISTOPHER P · 2015 to 2019
$903k
NIDDK NIH HHS K24 DK104676NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

Growth faltering in early childhood is prevalent in many low resource countries. Poor maternal dietary diversity during pregnancy has been linked with increased risk of fetal growth failure and adverse birth outcomes but may also influence subsequent infant growth. Our aim is to assess the role of prenatal maternal dietary diversity in infant growth in rural Uganda. Data from 3291 women and infant pairs enrolled in a birth cohort from 2014 to 2016 were analysed (NCT04233944). Maternal diets were assessed using dietary recall in the second or third trimesters of pregnancy. Maternal dietary diversity scores (DDS) were calculated using the FAO Minimum Dietary Diversity for Women (MDD-W). Cox regression models were used to evaluate associations of the DDS with the incidence of underweight, stunting and wasting in infants from 3 to 12 months, adjusting for confounding factors. The median DDS for women was low, at 3.0 (interquartile range 3.0-4.0), relative to the threshold of consuming five or more food groups daily. Infants of women in highest quartile of DDS (diverse diets) were less likely to be underweight (adjusted hazard ratio: 0.70, 95% confidence interval: 0.61, 0.80) compared with infants of women in Quartile 1 (p for trend <0.001) in models controlling for maternal factors. There was no significant association between DDS and stunting or wasting. Our findings suggest a relationship between higher maternal dietary diversity and lower risk of underweight in infancy. These findings suggest that programmes to improve infant growth could additionally consider strengthening prenatal dietary diversity to improve child outcomes globally.

Indexed as

ThinnessWasting SyndromeChildChild, PreschoolDietFemaleHumansInfantPregnancyUgandaVitaminsVitaminsinfant growthmaternal dietary diversityMDD-WprenatalstuntingUgandaunderweightwasting

Identifiers

PMID33595899
PMCPMC8189249
OpenAlexW3132021011

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.