ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021
Comparison of the anxiety, depression and their relationship to quality of life among adult acute leukemia patients and their family caregivers: a cross-sectional study in China.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Integral definition and conceptual model of mental health: Proposal from a systematic review of different paradigms.Frontiers in sociology · 2022Pooled it
- Effects of a WeChat-based multimodal psychoeducational intervention on psychological well-being and quality of life in acute leukaemia patients in China: a randomised controlled trial.Journal of cancer survivorship : research and practice · 2022Trial
- Quality of life dynamics in the gastric cancer dyad: an actor-partner interdependence model analysis guiding the development of a family-centered nursing framework.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Health-related Quality of Life in Patients Undergoing Ileal Ureter Replacement for Extensive Ureteral Stricture: A Prospective Multi-institutional Study.European urology open science · 2026Article
- Cognitive appraisal, negative coping, and family resilience among acute leukemia patients and their primary family caregivers: an actor-partner interdependence mediation model of quality of life.Frontiers in psychology · 2026Article
- Integrating Structured Peer Support Pathways for Patients Undergoing Cellular Therapies: Insights from a Participatory Study.Current oncology (Toronto, Ont.) · 2025Article
- Bidirectional relationship between anxiety disorder and cancer: a longitudinal population-based cohort study.BMC cancer · 2025Article
- Analysis of sleep disorders and their influencing factors in patients with ankylosing spondylitis.PloS one · 2025Article
- Symptom experiences and self-management strategies of patients with haematological malignancy undergoing chemotherapy: A qualitative study.Asia-Pacific journal of oncology nursing · 2024Article
- Effects of different psychological interventions on quality of life and remission rate in patients with acute leukemia receiving chemotherapy: A randomized controlled trial.Frontiers in psychology · 2023Article
- Short Sleep Duration as a Risk Factor for Depression, Anxiety and Fatigue in Patients with Leukemia.Neuropsychiatric disease and treatment · 2022Article
- Psychometric properties of the Chinese version of quality of life in life-threatening illness-family carer version.Frontiers in psychology · 2022Article
- Minimally invasive ureteroplasty with lingual mucosal graft for complex ureteral stricture: analysis of surgical and patient-reported outcomes.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo compare the anxiety, depression and explore their relationship to quality of life (QoL) among adult acute leukemia (AL) patients and family caregivers (FCs) in China.
methodsA multicenter cross-sectional study was conducted from April 2017 to January 2018. The sample comprised 207 dyads of adult AL patients and FCs. The participants were required to complete socio-demographic information and the Hospital Anxiety and Depression Scale (HADS). The Functional Assessment of Cancer Therapy-Leukemia (FACT-Leu, only for patients) and MOS 36-item Short-Form Health Survey (SF-36, only for FCs) were used to measure QoL.
resultsThe mean scores of anxiety and depression for AL patients were 7.89 ± 3.85 and 7.18 ± 4.23, respectively. For FCs, the mean scores of anxiety and depression were 9.96 ± 3.73 and 8.64 ± 3.74. In this study, adult AL Patients' sex, patients' depression score, whether patients achieving a CR or not, education, FCs' depression score, patients' social/family well-being and emotional well-being were significantly associated with patients' anxiety or depression (p < 0.05). For FCs, depression was significantly related to the physical component summary (β = 0.127, p = 0.008). There were significant differences in anxiety (t = - 5.92, p < 0.001) and depression (t = - 4.19, p < 0.001) between patients and FCs.
conclusionsAL patients' FCs showed higher score of anxiety and depression than that of patients. The psychological health may have a potential relationship between AL patients and their FCs. Healthcare professionals can conduct family-center interventions to improve mental health and QoL of AL patients and FCs.
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