Evidence map›Paper›PMID 33595796›Full record

ReviewEnvironmental science and pollution research international2021

Focus on Multi-targeted Role of Curcumin: a Boon in Therapeutic Paradigm.

Madhuri Grover, Tapan Behl, Monika Sachdeva, Simona Bungao, Lotfi Aleya, Dhruv Setia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Design of Polymeric Films for Antioxidant Active Food Packaging.International journal of molecular sciences · 2021
    Review
  7. In Vitro Phytochemical Screening, Cytotoxicity Studies ofMolecules (Basel, Switzerland) · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Madhuri GroverB.S. Anangpuria Institute of Pharmacy, Alampur, Haryana, India.
Tapan BehlChitkara College of Pharmacy, Chitkara University, Punjab, India. tapanbehl31@gmail.com.ORCID http://orcid.org/0000-0003-0993-7708
Monika SachdevaFatima College of Health Sciences, Al Ain, UAE.
Simona BungaoDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Lotfi AleyaChrono-Environment Laboratory, UMR CNRS 6249, Bourgogne Franche-Comté University, Besançon, France.
Dhruv SetiaChitkara College of Pharmacy, Chitkara University, Punjab, India.
Chitkara University · INAl Ain University · AECentre National de la Recherche Scientifique · FRUniversity of Oradea · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin is a polyphenolic compound that exhibited good anticancer potential against different types of cancers through its multi-targeted effect like the termination of cell proliferation, inflammation, angiogenesis, and metastasis, thereby acting as antiproliferative and cytotoxic in nature. The present review surveys the various drug combination tried with curcumin or its synthetic analogues and also the mechanism by which curcumin potentiates the effect of almost every drug. In addition, this article also focuses on aromatherapy which is gaining much popularity in cancer patients. After thoroughly studying several articles on combination therapy of curcumin through authenticated book chapters, websites, research, and review articles available at PubMed, ScienceDirect, etc., it has been observed that multi-targeted curcumin possess enormous anticancer potential and, with whatever drug it is given in combination, has always resulted in enhanced effect with reduced dose as well as side effects. It is also capable enough in overcoming the problem of chemoresistance. Besides this, aromatherapy also proved its potency in reducing cancer-related side effects. Combining all the factors together, we can conclude that combination therapy of drugs with curcumin should be explored extensively. In addition, aromatherapy can be used as an adjuvant or supplementary therapy to reduce the cancer complications in patients.

Indexed as

Antineoplastic AgentsCurcuminNeoplasmsCell ProliferationHumansAntineoplastic AgentsCurcuminAromatherapyCancerCombination therapyCurcuminMulti-targetTherapeutics

Identifiers

PMID33595796
OpenAlexW3130512751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.