SynthesisActa parasitologica2021
The Neglected Role of Trichomonas tenax in Oral Diseases: A Systematic Review and Meta-analysis.
Synthesis in Acta parasitologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Parasites in surgically removed appendices as a neglected public health concern: a systematic review and meta-analysis.Pathogens and global health · 2022Pooled it
- Global prevalence and epidemiology of Strongyloides stercoralis in dogs: a systematic review and meta-analysis.Parasites & vectors · 2022Pooled it
- Global prevalence of Trichomonas vaginalis among female sex workers: a systematic review and meta-analysis.Parasitology research · 2021Pooled it
- Investigation of Entamoeba gingivalis and Trichomonas tenax in gingivitis and periodontitis patients.BMC oral health · 2025Article
- Transmission Dynamics ofMicroorganisms · 2025Article
- Immunolocalization and 3D modeling of three unique proteins belonging to the costa of Tritrichomonas foetus.Parasitology research · 2025Article
- The potential of antimicrobial peptides to treat oral infections and cancer.Frontiers in medicine · 2025Review
- Frequency, socio-economic characteristics, and risk factors of oral cavity parasites in diabetes mellitus patients from Lorestan Province, Iran; a case-control study.Frontiers in cellular and infection microbiology · 2025Article
- Parasitological and molecular study ofArchives of Razi Institute · 2024Article
- Clinical implications of trichomonads detected in bronchoalveolar fluid by metagenomic next-generation sequencing: a multicenter retrospective study.Frontiers in cellular and infection microbiology · 2024Article
- Prevalence, socio-economic, and associated risk factors of oral cavity parasites in children with intellectual disability from Lorestan province, Iran.Frontiers in cellular and infection microbiology · 2024Article
- Comparative genomics betweenFrontiers in microbiology · 2024Article
- Molecular epidemiology and associated risk factors of oral cavity parasites in hemodialysis patients in western Iran.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- Article
- Trichomonas tenax induces barrier defects and modulates the inflammatory cytotoxicity of gingival and pulmonary epithelial cells.Parasite (Paris, France) · 2023Article
- Prevalence and risk factors of oral cavity parasites in pregnant women in Western Iran.Parasite epidemiology and control · 2022Article
- Draft Genome Sequence ofMicrobiology resource announcements · 2022Article
- A Loop-Mediated Isothermal Amplification (LAMP) Assay Specific toMicroorganisms · 2022Article
- Oral Colonization byFrontiers in cellular and infection microbiology · 2021Article
- Molecular Epidemiology and Associated Risk Factors of Parasites in Oral Cavity of Children with Malignancies in Western Iran.Iranian journal of parasitologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
purposeTrichomonas tenax (T. tenax) is a commensal flagellated protozoan found in periodontal microenvironment of the oral cavity, with a possible role in periodontal diseases. The purpose of the present systematic review and meta-analysis was to determine the worldwide prevalence of T. tenax infection and to show the neglected association of this parasitic infection with oral diseases.
methodsTo find literatures published until August 2020, five English databases (PubMed, Scopus, Science Direct, Web of Science and Google Scholar) were explored. Finally, 65 papers were qualified to be included in the current study.
resultsOur results revealed a global pooled prevalence of 17% (95% CI 14-22%) for T. tenax infection. The highest prevalence was estimated at 56% (42-69%) in Chile, while the lowest prevalence was related to Kenya with 3% (1-6%). The age-based analysis found that the infection was most common in 46-55 mean age group with 15% (0-100%). The overall prevalence regarding culture method, molecular method and direct method was 21% (12-32%), 19% (8-35%) and 17% (12-23%), respectively. Moreover, the subgroup analysis showed the pooled prevalence in patient with candidiasis [22% (3-52%)], gingivitis [21% (9-36%)] and periodontitis [27% (10-48%)].
conclusionOur study specified a connection between T. tenax protozoa and periodontitis disease. However, more epidemiological studies as well as clinical trials are needed to precisely identify this relation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.