Evidence map›Paper›PMID 33595744›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2021

International cost-effectiveness analysis evaluating endoscopic screening for gastric cancer for populations with low and high risk.

Benjamin Ascherman, Aaron Oh, Chin Hur

Abstract read
PubMed Publisher
In one paragraph

Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. The Cost-Effectiveness of Gastric Cancer Screening and Surveillance Among Average-Risk and Risk-Stratified Populations.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
  3. Screening for and surveillance of premalignant conditions of the stomach.Best practice & research. Clinical gastroenterology · 2025
    Review
  4. Article
  5. Article
  6. Integrating Salivary Biomarkers CST4 andClinical Medicine Insights. Oncology · 2025
    Article
  7. Review
  8. Health economic evaluation on population-basedChinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
  9. Article
  10. Article
  11. Promising Advances in LINC01116 Related to Cancer.Frontiers in cell and developmental biology · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benjamin AschermanVagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, Columbia University, 161 Fort Washington Avenue, New York, NY, 10032, USA. ba2461@columbia.edu.ORCID 0000-0003-4979-9856
Aaron OhDepartment of Medicine, Division of General Medicine, New York Presbyterian Columbia University Irving Medical Center, Columbia University, 622 West 168th Street, New York, NY, 10032, USA.
Chin HurVagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, Columbia University, 161 Fort Washington Avenue, New York, NY, 10032, USA.
Columbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer remains one of the 3 most common causes of cancer death worldwide. Understanding the health and economic factors that affect screening cost-effectiveness in different countries will help address when and where it makes most sense to screen for gastric cancer.

methodsWe performed a cost-effectiveness analysis using a Markov model to compare screening and surveillance strategies for gastric cancer in Brazil, France, Japan, Nigeria, and the United States. Primary outcome was the incremental cost-effectiveness ratio. We then performed a sensitivity analysis to determine how each variable affected the overall model.

resultsIn all countries, the most cost-effective strategies, measured by incremental cost-effectiveness ratio relative to no screening, were screening every 10 years, surveillance of high- and low-risk patients every 5 and 10 years, respectively, and screening every 5 years. Only Japan had at least one cost-effective screening strategy. The most important variables across different screening strategies and countries were starting age of screening, cost of endoscopy, and baseline probability of local gastric cancer at time of diagnosis.

conclusionsOur model suggests that screening for gastric cancer is cost-effective in countries with higher incidence and lower costs of screening, but screening may still be a viable option in high-risk populations within low incidence countries.

Indexed as

Population SurveillanceAdultAgedBrazilCost-Benefit AnalysisEarly Detection of CancerEndoscopy, GastrointestinalFemaleFranceHumansJapanMaleMarkov ChainsMiddle AgedNigeriaRisk AssessmentCost-effectivenessEndoscopyGastric cancer (GC)Quality adjusted life year (QALY)Screening

Identifiers

PMID33595744
OpenAlexW3130384603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.