Evidence map›Paper›PMID 33595641›Full record

ArticleJAMA2021

Vitamin D3 to Treat COVID-19: Different Disease, Same Answer.

David E Leaf, Adit A Ginde

Open access · greenAbstract readComment
In one paragraph

Article in JAMA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Therapeutic advances in COVID-19.Nature reviews. Nephrology · 2023
    Review
  11. Review
  12. Article
  13. Observational
  14. Review
  15. Hallmarks of Severe COVID-19 Pathogenesis:Frontiers in immunology · 2022
    Review
  16. The effect ofFrontiers in pharmacology · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

David E LeafDivision of Renal Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Adit A GindeDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora.
Brigham and Women's Hospital · USUniversity of Colorado Denver · US

Funding

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7M
Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Deferoxamine for the Prevention of Acute Kidney InjuryR01DK125786 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI LEAF, DAVID EVAN · 2020 to 2024
$3.5M
Enhancing the Surrogate Informed Consent Process for Critical Care ResearchU01HL123010 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI GINDE, ADIT A., MOSS, MARC · 2014 to 2020
$2.6M
Precision Medicine Approach to Vitamin D3 Administration in Critical IllnessR01HL144566 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LEAF, DAVID EVAN · 2019 to 2022
$1.8M
The Impact of Fluid Resuscitation on Glycocalyx Degradation in Septic ShockR01HL149422 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SCHMIDT, ERIC PETER, SHAPIRO, NATHAN I · 2019 to 2022
$1.7M
NCATS NIH HHS UL1 TR002243NHLBI NIH HHS OT2 HL156812NHLBI NIH HHS R01 HL144566NHLBI NIH HHS R01 HL149422NHLBI NIH HHS U01 HL123010NIDDK NIH HHS R01 DK125786
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CholecalciferolCOVID-19HospitalsHumansLength of StaySARS-CoV-2Vitamin DCholecalciferolVitamin D

Identifiers

PMID33595641
PMCPMC8412177
OpenAlexW3132383336

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.