ArticleIndian journal of ophthalmology2021
Severe ocular and adnexal complications in dengue hemorrhagic fever: A report of 29 eyes.
Article in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Dengue Fever Complicated by Acute Angle-closure Glaucoma and Endophthalmitis.Annals of African medicine · 2026Article
- Dengue-Related Ocular Complications: Spectrum, Diagnosis, and Management.Pathogens (Basel, Switzerland) · 2025Review
- Computed tomography imaging and clinical significance of bacterium-positive pulmonary tuberculosis complicated with diabetes.World journal of clinical cases · 2024Article
- Causes of Vision Loss Associated with Dengue Fever in Bihar, India - A Case Series.The American journal of tropical medicine and hygiene · 2024Article
- Dengue.Lancet (London, England) · 2024Review
- Commentary: Evidence of dengue virus in eviscerated specimens of panophthalmitis secondary to dengue fever: A possible cause-effect phenomenon.Indian journal of ophthalmology · 2022Article
- An update on the ocular manifestations of dengue.Taiwan journal of ophthalmologyReview
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Authors and funding
7 authors at 1 institution in 1 country.
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Abstract
Purpose: To describe a series of sight-threatening ocular and adnexal involvement associated with dengue hemorrhagic fever and their treatment options. Methods: Retrospective, interventional, non-comparative case series. Medical records of patients who presented with ocular symptoms attributed to dengue hemorrhagic fever were reviewed. Demography, presenting features, and treatment outcomes were recorded. Outcome measures assessed included globe salvage, vision salvage, and visual improvement. The outcome was deemed as favorable if vision salvage was possible and unfavorable if the vision was lost. Results: Twenty-nine eyes of 23 patients were included. Bilateral ocular involvement was seen in 6 (26%) patients. The mean age was 37.62 ± 18.68 years (range: 14 to 81 years). Coexistent diabetes mellitus and enteric fever were present in three patients. History of blood transfusion was present in nine (40%) and thrombocytopenia in eight (35%) patients at the time of presentation with ocular complaints. Presenting features included endophthalmitis in 11 (38%), panophthalmitis in 10 (35%), orbital cellulitis with panophthalmitis in four (14%), isolated corneal or scleral melt in three (10%), and orbital hemorrhage with panophthalmitis in one (3%) patient. Globe salvage was achieved in 21/29 eyes (72.4%), vision salvage in 6/29 eyes (20.68%), and improvement in visual acuity was noted in 5/29 eyes (17.24%). Logistic regression analysis revealed no significant effect of any clinical-microbiological factors on globe salvage, vision salvage, and visual improvement. However, visual improvement and globe salvage were possible in eyes that underwent early endoscopic vitrectomy. Conclusion: Dengue fever can present with sight-threatening ocular and adnexal inflammation resulting in endophthalmitis and panophthalmitis, orbital cellulitis, corneal and scleral melt, and orbital hemorrhage. Early vitrectomy may improve vision and globe salvage in cases with significant vitritis.
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