Evidence map›Paper›PMID 33595445›Full record

Observational studyJournal of medical Internet research2021

Sociodemographic, Health and Lifestyle, Sampling, and Mental Health Determinants of 24-Hour Motor Activity Patterns: Observational Study.

Sonia Difrancesco, Harriëtte Riese, Kathleen R Merikangas, Haochang Shou, Vadim Zipunnikov, Niki Antypa, Albert M van Hemert, Robert A Schoevers, Brenda W J H Penninx, Femke Lamers

Abstract readObservational Study
In one paragraph

Observational study in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Association between Daily Pattern of Physical Activity and Depression: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. U.S. Adolescent Rest-Activity patterns: insights from functional principal component analysis (NHANES 2011-2014).The international journal of behavioral nutrition and physical activity · 2023
    Article
  6. Association between circadian physical activity patterns and mortality in the UK Biobank.The international journal of behavioral nutrition and physical activity · 2023
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sonia DifrancescoAmsterdam Public Health Research Institute, Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands.ORCID 0000-0001-7254-3686
Harriëtte RieseInterdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, Universitair Medisch Centrum Groningen, University of Groningen, Groningen, Netherlands.ORCID 0000-0003-3661-3151
Kathleen R MerikangasGenetic Epidemiology Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, United States.ORCID 0000-0002-1501-9949
Haochang ShouDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, United States.ORCID 0000-0002-3043-047X
Vadim ZipunnikovDepartment of Biostatistics, Johns Hopkins University, Baltimore, MD, United States.ORCID 0000-0001-9864-2420
Niki AntypaDepartment of Clinical Psychology, Institute of Psychology, Leiden University, Leiden, Netherlands.ORCID 0000-0001-9343-8842
Albert M van HemertDepartment of Psychiatry, Leiden University Medical Center, Leiden, Netherlands.ORCID 0000-0003-3421-355X
Robert A SchoeversInterdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, Universitair Medisch Centrum Groningen, University of Groningen, Groningen, Netherlands.ORCID 0000-0003-0760-9866
Brenda W J H PenninxAmsterdam Public Health Research Institute, Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands.ORCID 0000-0001-7779-9672
Femke LamersAmsterdam Public Health Research Institute, Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands.ORCID 0000-0003-4344-5766

Funding

Motor Activity Research Consortium for Health (mMarch)ZIAMH002954 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MERIKANGAS, KATHLEEN R · 2016 to 2025
$10.1M
Intramural NIH HHS ZIA MH002954
6 · The paper itself

Abstract

backgroundAnalyzing actigraphy data using standard circadian parametric models and aggregated nonparametric indices may obscure temporal information that may be a hallmark of the circadian impairment in psychiatric disorders. Functional data analysis (FDA) may overcome such limitations by fully exploiting the richness of actigraphy data and revealing important relationships with mental health outcomes. To our knowledge, no studies have extensively used FDA to study the relationship between sociodemographic, health and lifestyle, sampling, and psychiatric clinical characteristics and daily motor activity patterns assessed with actigraphy in a sample of individuals with and without depression/anxiety.

objectiveWe aimed to study the association between daily motor activity patterns assessed via actigraphy and (1) sociodemographic, health and lifestyle, and sampling factors, and (2) psychiatric clinical characteristics (ie, presence and severity of depression/anxiety disorders).

methodsWe obtained 14-day continuous actigraphy data from 359 participants from the Netherlands Study of Depression and Anxiety with current (n=93), remitted (n=176), or no (n=90) depression/anxiety diagnosis, based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition. Associations between patterns of daily motor activity, quantified via functional principal component analysis (fPCA), and sociodemographic, health and lifestyle, sampling, and psychiatric clinical characteristics were assessed using generalized estimating equation regressions. For exploratory purposes, function-on-scalar regression (FoSR) was applied to quantify the time-varying association of sociodemographic, health and lifestyle, sampling, and psychiatric clinical characteristics on daily motor activity.

resultsFour components of daily activity patterns captured 77.4% of the variability in the data: overall daily activity level (fPCA1, 34.3% variability), early versus late morning activity (fPCA2, 16.5% variability), biphasic versus monophasic activity (fPCA3, 14.8% variability), and early versus late biphasic activity (fPCA4, 11.8% variability). A low overall daily activity level was associated with a number of sociodemographic, health and lifestyle, and psychopathology variables: older age (P<.001), higher education level (P=.005), higher BMI (P=.009), greater number of chronic diseases (P=.02), greater number of cigarettes smoked per day (P=.02), current depressive and/or anxiety disorders (P=.05), and greater severity of depressive symptoms (P<.001). A high overall daily activity level was associated with work/school days (P=.02) and summer (reference: winter; P=.03). Earlier morning activity was associated with older age (P=.02), having a partner (P=.009), work/school days (P<.001), and autumn and spring (reference: winter; P=.02 and P<.001, respectively). Monophasic activity was associated with older age (P=.005). Biphasic activity was associated with work/school days (P<.001) and summer (reference: winter; P<.001). Earlier biphasic activity was associated with older age (P=.005), work/school days (P<.001), and spring and summer (reference: winter; P<.001 and P=.005, respectively). In FoSR analyses, age, work/school days, and season were the main determinants having a time-varying association with daily motor activity (all P<.05).

conclusionsFeatures of daily motor activity extracted with fPCA reflect commonly studied factors such as the intensity of daily activity and preference for morningness/eveningness. The presence and severity of depression/anxiety disorders were found to be associated mainly with a lower overall activity pattern but not with the time of the activity. Age, work/school days, and season were the variables most strongly associated with patterns and time of activity, and thus future epidemiological studies on motor activity in depression/anxiety should take these variables into account.

Indexed as

FemaleHumansLife StyleMaleMental HealthMiddle AgedMotor ActivitySocioeconomic FactorsTime Factorsactigraphyactivityfunctional data analysismental healthwell-being

Identifiers

PMID33595445
PMCPMC7929740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.