Evidence map›Paper›PMID 33595276›Full record

ArticleACS chemical biology2021

Pseudomonas Virulence Factor Pathway Synthesizes Autoinducers That Regulate the Secretome of a Pathogen.

Ashley M Kretsch, Gina L Morgan, Katie A Acken, Sarah A Barr, Bo Li

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Anti-QS Strategies AgainstMicroorganisms · 2025
    Review
  4. Article
  5. Article
  6. ACS chemical biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Small NRPS-like enzymes inFrontiers in fungal biology · 2022
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ashley M Kretsch
Gina L Morgan
Katie A Acken
Sarah A Barr
University of North Carolina at Chapel Hill · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Mining Genomes for Synergistic AntibioticsDP2HD094657 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LI, BO · 2017 to 2017
$2.3M
NCI NIH HHS P30 CA016086NICHD NIH HHS DP2 HD094657
6 · The paper itself

Abstract

Cell-to-cell communication via chemical signals is an essential mechanism that pathogenic bacteria use to coordinate group behaviors and promote virulence. The

Indexed as

Bacterial ProteinsCell ExtractsGene Expression Regulation, BacterialOxazolesPseudomonasQuorum SensingSecondary MetabolismSignal TransductionTranscription FactorsVirulenceVirulence Factors2-isobutyl-5-(3-indolyl)oxazole2-n-pentyl-5-(3-indolyl)oxazoleBacterial ProteinsCell ExtractsOxazolespimprinineTranscription FactorsVirulence Factors

Identifiers

PMID33595276
PMCPMC8164881
OpenAlexW3131549868

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.